AIM: To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B. METHODS: The levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole. RESULTS: After one course of treatment with liniment levamisole, the levels of CD3(+), CD4(+), and the ratio of CD4(+)/CD8(+) increased as compared to those before the treatment but the level of CD8(+) decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole. CONCLUSION:Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.
RCT Entities:
AIM: To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B. METHODS: The levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole. RESULTS: After one course of treatment with liniment levamisole, the levels of CD3(+), CD4(+), and the ratio of CD4(+)/CD8(+) increased as compared to those before the treatment but the level of CD8(+) decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole. CONCLUSION:Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.
Authors: M Artwohl; T Hölzenbein; L Wagner; A Freudenthaler; W Waldhäusl; S M Baumgartner-Parzer Journal: Br J Pharmacol Date: 2000-12 Impact factor: 8.739
Authors: Ahmed F Donia; Galal M Amer; Hassan A Ahmed; Sanaa H Gazareen; Fatma E Moustafa; Ahmed A Shoeib; Amani M Ismail; Said Khamis; Mohamed A Sobh Journal: Pediatr Nephrol Date: 2002-05 Impact factor: 3.714