Literature DB >> 16437156

Phosphoinositide 3-kinase controls early and late events in mammalian cell division.

Zaira García1, Amit Kumar, Miriam Marqués, Isabel Cortés, Ana C Carrera.   

Abstract

Phosphoinositide 3-kinase (PI3K) plays a crucial role in triggering cell division. To initiate this process, PI3K induces two distinct routes, of which one promotes cell growth and the other regulates cyclin-dependent kinases. Fine-tuned PI3K regulation is also required for later cell cycle phases. Here, we review the multiple points at which PI3K controls cell division and discuss its impact on human cancer.

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Year:  2006        PMID： 16437156      PMCID： PMC1383550          DOI： 10.1038/sj.emboj.7600967

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  64 in total

1.  Phosphoinositide 3-kinase activation regulates cell division time by coordinated control of cell mass and cell cycle progression rate.

Authors:  Beatriz Alvarez; Elia Garrido; Jose A Garcia-Sanz; Ana C Carrera
Journal:  J Biol Chem       Date:  2003-04-21       Impact factor: 5.157

2.  The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras.

Authors:  Concepcion Jimenez; Carmen Hernandez; Belen Pimentel; Ana C Carrera
Journal:  J Biol Chem       Date:  2002-08-23       Impact factor: 5.157

Review 3.  The interaction of glycogen synthase kinase-3 (GSK-3) with the cell cycle.

Authors:  W Jonathan Ryves; Adrian J Harwood
Journal:  Prog Cell Cycle Res       Date:  2003

Review 4.  Phosphoinositide 3-kinase in disease: timing, location, and scaffolding.

Authors:  Matthias P Wymann; Romina Marone
Journal:  Curr Opin Cell Biol       Date:  2005-04       Impact factor: 8.382

5.  Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation.

Authors:  Miri Stolovich; Hua Tang; Eran Hornstein; Galit Levy; Ruth Cohen; Sun Sik Bae; Morris J Birnbaum; Oded Meyuhas
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

6.  Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells.

Authors:  Ludmila Jirmanova; Marielle Afanassieff; Stéphanie Gobert-Gosse; Suzy Markossian; Pierre Savatier
Journal:  Oncogene       Date:  2002-08-15       Impact factor: 9.867

7.  TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.

Authors:  Ken Inoki; Yong Li; Tianquan Zhu; Jun Wu; Kun-Liang Guan
Journal:  Nat Cell Biol       Date:  2002-09       Impact factor: 28.824

8.  Requirement for phosphatidylinositol-3 kinase activity during progression through S-phase and entry into mitosis.

Authors:  Surabhi Dangi; Hyukjin Cha; Paul Shapiro
Journal:  Cell Signal       Date:  2003-07       Impact factor: 4.315

9.  Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1.

Authors:  Angela Romanelli; Valley C Dreisbach; John Blenis
Journal:  J Biol Chem       Date:  2002-08-14       Impact factor: 5.157

Review 10.  The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network.

Authors:  Lindsey D Mayo; David B Donner
Journal:  Trends Biochem Sci       Date:  2002-09       Impact factor: 13.807
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  46 in total

1.  The expression of Akt and ERK1/2 proteins decreased in dexamethasone-induced intrauterine growth restricted rat placental development.

Authors:  Asli Ozmen; Gozde Unek; Dijle Kipmen-Korgun; Emin Turkay Korgun
Journal:  J Mol Histol       Date:  2011-04-23       Impact factor: 2.611

Review 2.  The emerging mechanisms of isoform-specific PI3K signalling.

Authors:  Bart Vanhaesebroeck; Julie Guillermet-Guibert; Mariona Graupera; Benoit Bilanges
Journal:  Nat Rev Mol Cell Biol       Date:  2010-04-09       Impact factor: 94.444

3.  Antibiotic drug tigecycline reduces neuroblastoma cells proliferation by inhibiting Akt activation in vitro and in vivo.

Authors:  Xiaoxia Zhong; Erhu Zhao; Chunling Tang; Weibo Zhang; Juan Tan; Zhen Dong; Han-Fei Ding; Hongjuan Cui
Journal:  Tumour Biol       Date:  2015-12-19

4.  Phosphoinositide 3-kinase activation in late G1 is required for c-Myc stabilization and S phase entry.

Authors:  Amit Kumar; Miriam Marqués; Ana C Carrera
Journal:  Mol Cell Biol       Date:  2006-10-02       Impact factor: 4.272

5.  P. gingivalis accelerates gingival epithelial cell progression through the cell cycle.

Authors:  Masae Kuboniwa; Yoshiaki Hasegawa; Song Mao; Satoshi Shizukuishi; Atsuo Amano; Richard J Lamont; Ozlem Yilmaz
Journal:  Microbes Infect       Date:  2007-10-26       Impact factor: 2.700

6.  Src regulates cell cycle protein expression and renal epithelial cell proliferation via PI3K/Akt signaling-dependent and -independent mechanisms.

Authors:  Jingping Xing; Zhu Zhang; Haiping Mao; Rick G Schnellmann; Shougang Zhuang
Journal:  Am J Physiol Renal Physiol       Date:  2008-04-23

7.  Gadolinium-promoted cell cycle progression with enhanced S-phase entry via activation of both ERK and PI3K signaling pathways in NIH 3T3 cells.

Authors:  Li-Juan Fu; Jin-Xia Li; Xiao-Gai Yang; Kui Wang
Journal:  J Biol Inorg Chem       Date:  2008-10-25       Impact factor: 3.358

8.  Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.

Authors:  Miriam Marqués; Amit Kumar; Isabel Cortés; Ana Gonzalez-García; Carmen Hernández; M Carmen Moreno-Ortiz; Ana C Carrera
Journal:  Mol Cell Biol       Date:  2008-02-19       Impact factor: 4.272

9.  A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells.

Authors:  Lisa Salazar; Tamara Kashiwada; Pavel Krejci; Paul Muchowski; Daniel Donoghue; William R Wilcox; Leslie Michels Thompson
Journal:  Hum Mol Genet       Date:  2009-03-13       Impact factor: 6.150

10.  miR-638 Inhibits immature Sertoli cell growth by indirectly inactivating PI3K/AKT pathway via SPAG1 gene.

Authors:  Pandi Hu; Kaifeng Guan; Yue Feng; Changping Ma; Huibin Song; Yang Li; Xuanyan Xia; Jialian Li; Fenge Li
Journal:  Cell Cycle       Date:  2017-11-09       Impact factor: 4.534
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