Literature DB >> 16437049

MRI in the acute phase of spinal cord traumatic lesions: Relationship between MRI findings and neurological outcome.

Chiara Andreoli1, Maria Chiara Colaiacomo, Mario Rojas Beccaglia, Claudio Di Biasi, Emanuele Casciani, Gianfranco Gualdi.   

Abstract

PURPOSE: To evaluate the role of emergency MRI in the diagnosis of acute spinal injuries, and to correlate the MRI pattern with the neurological outcome.
MATERIALS AND METHODS: Thirty-eight patients with MRI-proven spinal cord injury were classified according to the Frankel classification. MRI was always performed within 8 hours from trauma. Frankel classification divides spinal cord injuries into 5 classes of decreasing severity based on the presence of motor and/or sensory function loss. On the basis of the MRI findings the patients were classified in 3 groups: group 1 (intramedullary haematoma), group 2 (multi-metamer oedema), group 3 (single-metamer oedema). All patients underwent neurosurgery and were clinically evaluated until the stabilization of neurological recovery. Mean follow-up time was 12 months. The MR images were retrospectively evaluated and correlated to the neurological outcome.
RESULTS: Twenty-eight patients showed complete motor loss (Frankel classes A and B); of these 28 patients 12 (42.8%) had MRI evidence of intramedullary haematoma, 12 (42.8%) had multi-metamer oedema and 4 (14.4%) had single-metamer oedema. Of the 10 patients with incomplete motor loss, none had MRI evidence of haemorrhage, 4 (40%) showed multi-metamer oedema and 6 (60%) showed single-metamer oedema. Follow-up clinical assessment revealed that 14/38 patients (36,8%) had clinical improvement and 2/38 cases (5%) had a complete motor recovery, as demonstrated by the move to a higher Frankel class.
CONCLUSIONS: Our results, consistent with previous reports, confirm a strong correlation between the MRI appearance of traumatic spinal cord injuries in acute phase and long-term recovery of motor and sensory function: patients with initial haemorrhage had a poor prognosis, whereas those with spinal cord oedema had a good clinical outcome, as demonstrated by the passage to a higher Frankel class. MRI is particularly important in the initial evaluation of unconscious patients who cannot undergo a motor and sensory neurological evaluation, and to define the prognosis, which will influence the correct therapeutic choice.

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Mesh:

Year:  2005        PMID: 16437049

Source DB:  PubMed          Journal:  Radiol Med        ISSN: 0033-8362            Impact factor:   3.469


  18 in total

Review 1.  The role of magnetic resonance imaging in the management of acute spinal cord injury.

Authors:  Anthony Bozzo; Judith Marcoux; Mohan Radhakrishna; Julie Pelletier; Benoit Goulet
Journal:  J Neurotrauma       Date:  2010-08-30       Impact factor: 5.269

2.  Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury.

Authors:  J Haefeli; M C Mabray; W D Whetstone; S S Dhall; J Z Pan; P Upadhyayula; G T Manley; J C Bresnahan; M S Beattie; A R Ferguson; J F Talbott
Journal:  AJNR Am J Neuroradiol       Date:  2016-12-22       Impact factor: 3.825

3.  Evaluation of Traumatic Spine by Magnetic Resonance Imaging and Correlation with Neurological Recovery.

Authors:  Sarita Magu; Deepak Singh; Rohtas Kanwar Yadav; Manju Bala
Journal:  Asian Spine J       Date:  2015-09-22

4.  Intramedullary Lesion Length on Postoperative Magnetic Resonance Imaging is a Strong Predictor of ASIA Impairment Scale Grade Conversion Following Decompressive Surgery in Cervical Spinal Cord Injury.

Authors:  Bizhan Aarabi; Charles A Sansur; David M Ibrahimi; J Marc Simard; David S Hersh; Elizabeth Le; Cara Diaz; Jennifer Massetti; Noori Akhtar-Danesh
Journal:  Neurosurgery       Date:  2017-04-01       Impact factor: 4.654

5.  Multiparametric MRI reveals dynamic changes in molecular signatures of injured spinal cord in monkeys.

Authors:  Feng Wang; Hui-Xin Qi; Zhongliang Zu; Arabinda Mishra; Chaohui Tang; John C Gore; Li Min Chen
Journal:  Magn Reson Med       Date:  2014-10-21       Impact factor: 4.668

6.  Longitudinal assessment of spinal cord injuries in nonhuman primates with quantitative magnetization transfer.

Authors:  Feng Wang; Ke Li; Arabinda Mishra; Daniel Gochberg; Li Min Chen; John C Gore
Journal:  Magn Reson Med       Date:  2015-05-08       Impact factor: 4.668

7.  Traumatic cervical spinal cord injury: relationship of MRI findings to initial neurological impairment.

Authors:  Chen Jin; Lijuan Zhao; Jinhui Wu; Lianshun Jia; Liming Cheng; Ning Xie
Journal:  Eur Spine J       Date:  2021-09-20       Impact factor: 3.134

8.  Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury.

Authors:  Marc C Mabray; Jason F Talbott; William D Whetstone; Sanjay S Dhall; David B Phillips; Jonathan Z Pan; Geoffrey T Manley; Jacqueline C Bresnahan; Michael S Beattie; Jenny Haefeli; Adam R Ferguson
Journal:  J Neurotrauma       Date:  2016-02-01       Impact factor: 5.269

9.  Intramedullary lesion expansion on magnetic resonance imaging in patients with motor complete cervical spinal cord injury.

Authors:  Bizhan Aarabi; J Marc Simard; Joseph A Kufera; Melvin Alexander; Katie M Zacherl; Stuart E Mirvis; Kathirkamanthan Shanmuganathan; Gary Schwartzbauer; Christopher M Maulucci; Justin Slavin; Khawar Ali; Jennifer Massetti; Howard M Eisenberg
Journal:  J Neurosurg Spine       Date:  2012-07-13

10.  MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis.

Authors:  Hamdy Awad; Anna Bratasz; Gerard Nuovo; Richard Burry; Xiaomei Meng; Hesham Kelani; Melissa Brown; Mohamed E Ramadan; Jim Williams; Lamia Bouhliqah; Phillip G Popovich; Zhen Guan; Cynthia Mcallister; Sarah E Corcoran; Brian Kaspar; D Michele Basso; José J Otero; Claudia Kirsch; Ian C Davis; Carlo Maria Croce; Jean-Jacques Michaille; Esmerina Tili
Journal:  Ann Diagn Pathol       Date:  2018-06-18       Impact factor: 2.090

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