Literature DB >> 16436991

Intratumoral and brainstem hemorrhage in a patient with vestibular schwannoma and oral anticoagulant therapy.

Jean-François Vellin1, Alexis Bozorg Grayeli, Michel Kalamarides, Cyril Fond, Didier Bouccara, Olivier Sterkers.   

Abstract

OBJECTIVE: To report the first case of spontaneous intratumoral and brainstem hemorrhage in a patient with a vestibular schwannoma. STUDY
DESIGN: Case report and review of the literature.
SETTING: University-based, tertiary referral center. PATIENT: A 73-year-old woman with a vestibular schwannoma, anti-vitamin K overdose, and arterial hypertension experienced a rapid onset of headache, facial palsy, diplopia, and hoarseness.
INTERVENTIONS: The patient was admitted to the intensive care unit and treated with vitamin K and corticoids. MAIN OUTCOME MEASURES: Clinical and radiologic findings.
RESULTS: At admission, the magnetic resonance imaging and computed tomographic scans showed an intratumoral hemorrhage. The patient entered a coma 24 hours after the onset of the symptoms. At that time, the computed tomographic scan demonstrated a massive intratumoral and brainstem hemorrhage. The patient died 3 days later.
CONCLUSION: Intratumoral, subarachnoid, and brainstem hemorrhages can occur in patients with vestibular schwannoma. Oral anticoagulant therapy is a risk factor for tumor-related hemorrhage.

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Year:  2006        PMID: 16436991     DOI: 10.1097/01.mao.0000188339.45772.be

Source DB:  PubMed          Journal:  Otol Neurotol        ISSN: 1531-7129            Impact factor:   2.311


  3 in total

1.  RAD51 Inhibitor and Radiation Toxicity in Vestibular Schwannoma.

Authors:  Torin P Thielhelm; Aida Nourbakhsh; Scott M Welford; Eric A Mellon; Olena Bracho; Michael E Ivan; Fred Telischi; Cristina Fernandez-Valle; Christine T Dinh
Journal:  Otolaryngol Head Neck Surg       Date:  2022-03-01       Impact factor: 5.591

2.  A Unique Pediatric Case of Intratumoral Hemorrhage in a Sporadic Vestibular Schwannoma.

Authors:  Batuk Diyora; Bhagyashri Bhende; Nitin Kotecha; Mazharkhan Mulla; Gagan Dhal; Naren Nayak
Journal:  J Pediatr Neurosci       Date:  2019-09-27

3.  The Clinical Implications of Spontaneous Hemorrhage in Vestibular Schwannomas.

Authors:  Christopher S Hong; Lan Jin; Wyatt B David; Brian Shear; Amy Y Zhao; Yawei Zhang; E Zeynep Erson-Omay; Robert K Fulbright; Anita Huttner; John Kveton; Jennifer Moliterno
Journal:  J Neurol Surg B Skull Base       Date:  2020-03-16
  3 in total

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