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Literature DB >> 16436753

Piperine, a phytochemical potentiator of ciprofloxacin against Staphylococcus aureus.

Inshad Ali Khan¹, Zahid Mehmood Mirza, Ashwani Kumar, Vijeshwar Verma, Ghulam Nabi Qazi.

Abstract

Piperine, a trans-trans isomer of 1-piperoyl-piperidine, in combination with ciprofloxacin markedly reduced the MICs and mutation prevention concentration of ciprofloxacin for Staphylococcus aureus, including methicillin-resistant S. aureus. The enhanced accumulation and decreased efflux of ethidium bromide in the wild-type and mutant (CIPr-1) strains in the presence of piperine suggest its involvement in the inhibition of bacterial efflux pumps.

Entities: Chemical Species

Mesh：

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Year: 2006 PMID： 16436753 PMCID： PMC1366922 DOI： 10.1128/AAC.50.2.810-812.2006

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

17 in total

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5. Relative potential for selection of fluoroquinolone-resistant Streptococcus pneumoniae strains by levofloxacin: comparison with ciprofloxacin, sparfloxacin and ofloxacin.

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Journal: J Antimicrob Chemother Date: 1999-06 Impact factor: 5.790

Review 6. NCCLS perspectives in changing susceptibility breakpoints for antimicrobial drugs.

Authors: John G Gums
Journal: Int J Antimicrob Agents Date: 2003-10 Impact factor: 5.283

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Authors: Rajinder K Bhardwaj; Hartmut Glaeser; Laurent Becquemont; Ulrich Klotz; Suresh K Gupta; Martin F Fromm
Journal: J Pharmacol Exp Ther Date: 2002-08 Impact factor: 4.030

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Journal: J Bacteriol Date: 1991-09 Impact factor: 3.490

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Authors: Simon Gibbons; Moyosoluwa Oluwatuyi; Glenn W Kaatz
Journal: J Antimicrob Chemother Date: 2003-01 Impact factor: 5.790

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Journal: J Pharmacol Exp Ther Date: 1985-01 Impact factor: 4.030

32 in total

Review 1. Efflux-mediated drug resistance in bacteria: an update.

Authors: Xian-Zhi Li; Hiroshi Nikaido
Journal: Drugs Date: 2009-08-20 Impact factor: 9.546

2. Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes β-catenin mediated oncogenesis and IL-8 secretion in vitro.

Authors: Nagendran Tharmalingam; Min Park; Min Ho Lee; Hyun Jun Woo; Hyun Woo Kim; Ji Yeong Yang; Ki-Jong Rhee; Jong-Bae Kim
Journal: Am J Transl Res Date: 2016-02-15 Impact factor: 4.060

3. Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal).

Authors: Emily R Britton; Joshua J Kellogg; Olav M Kvalheim; Nadja B Cech
Journal: J Nat Prod Date: 2017-11-01 Impact factor: 4.050

4. Inhibition of bacterial multidrug resistance by celecoxib, a cyclooxygenase-2 inhibitor.

Authors: Arunasree M Kalle; Arshad Rizvi
Journal: Antimicrob Agents Chemother Date: 2010-10-11 Impact factor: 5.191

5. Inhibitory and resistance-modifying potential of plant-based alkaloids against methicillin-resistant Staphylococcus aureus (MRSA).

Authors: Mastura Mohtar; Saiful Azmi Johari; Abdul Rashid Li; Mazurah Mohamed Isa; Shuhaimi Mustafa; Abdul Manaf Ali; Dayang Fredalina Basri
Journal: Curr Microbiol Date: 2009-05-28 Impact factor: 2.188

6. The toxic effects of piperine against Trypanosoma cruzi: ultrastructural alterations and reversible blockage of cytokinesis in epimastigote forms.

Authors: Leonardo Freire-de-Lima; Tatiana Santana Ribeiro; Gustavo Miranda Rocha; Bruno Alves Brandão; Alexandre Romeiro; Lucia Mendonça-Previato; José Osvaldo Previato; Marco Edilson Freire de Lima; Técia Maria Ulisses de Carvalho; Norton Heise
Journal: Parasitol Res Date: 2008-01-29 Impact factor: 2.289