Literature DB >> 16435855

Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions.

Jasmina Nikodinovic1, Jennifer M Dinges, Stephen C Bergmeier, Mark C McMills, Dennis L Wright, Nigel D Priestley.   

Abstract

[reaction: see text]. An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.

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Year:  2006        PMID： 16435855     DOI： 10.1021/ol052739p

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis.

Authors:  Joshua B Phillips; Adrienne E Smith; Brian R Kusche; Bradley A Bessette; P Whitney Swain; Stephen C Bergmeier; Mark C McMills; Dennis L Wright; Nigel D Priestley
Journal:  Bioorg Med Chem Lett       Date:  2010-07-07       Impact factor: 2.823

2.  Alternating pattern of stereochemistry in the nonactin macrocycle is required for antibacterial activity and efficient ion binding.

Authors:  Brian R Kusche; Adrienne E Smith; Michele A McGuirl; Nigel D Priestley
Journal:  J Am Chem Soc       Date:  2009-12-02       Impact factor: 15.419

Review 3.  Rhodococcus as A Versatile Biocatalyst in Organic Synthesis.

Authors:  Hanna Busch; Peter-Leon Hagedoorn; Ulf Hanefeld
Journal:  Int J Mol Sci       Date:  2019-09-26       Impact factor: 5.923
  3 in total

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