Literature DB >> 16435849

A concise total synthesis of naamidine A.

Nicholas S Aberle1, Guillaume Lessene, Keith G Watson.   

Abstract

[reaction: see text]. A total synthesis of naamidine A is reported. Key benefits of the described pathway include its brevity, its synthetic ease, and its flexibility with respect to the preparation of analogues. Formation of the 2-aminoimidazole core is achieved by condensation of the appropriate alpha-aminoketone with cyanamide.

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Year:  2006        PMID: 16435849     DOI: 10.1021/ol052568o

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  6 in total

1.  Total syntheses of isonaamine C and isonaamidine E.

Authors:  Heather M Lima; Beatriz J Garcia-Barboza; Nicole N Khatibi; Carl J Lovely
Journal:  Tetrahedron Lett       Date:  2011-11-02       Impact factor: 2.415

2.  Total syntheses and cytotoxicity of kealiiquinone, 2-deoxy-2-aminokealiiquinone and analogs.

Authors:  Jayanta Das; Arunoday Bhan; Subhrangsu S Mandal; Carl J Lovely
Journal:  Bioorg Med Chem Lett       Date:  2013-09-06       Impact factor: 2.823

3.  Total Syntheses of Naamidine G and 14-Methoxynaamidine G.

Authors:  Panduka B Koswatta; Carl J Lovely
Journal:  Tetrahedron Lett       Date:  2010-01-06       Impact factor: 2.415

4.  Synthesis of Naamidine A and Selective Access to N(2)-Acyl-2-aminoimidazole Analogues.

Authors:  Joseph B Gibbons; Justin M Salvant; Rachel M Vaden; Ki-Hyeok Kwon; Bryan E Welm; Ryan E Looper
Journal:  J Org Chem       Date:  2015-09-24       Impact factor: 4.354

Review 5.  Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment.

Authors:  Magbubah Essack; Vladimir B Bajic; John A C Archer
Journal:  Mar Drugs       Date:  2011-09-20       Impact factor: 6.085

6.  In Silico Evaluation of Antifungal Compounds from Marine Sponges against COVID-19-Associated Mucormycosis.

Authors:  Omkar Pokharkar; Hariharan Lakshmanan; Grigory Zyryanov; Mikhail Tsurkan
Journal:  Mar Drugs       Date:  2022-03-20       Impact factor: 5.118

  6 in total

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