Literature DB >> 16435485

Depression of insulin release by anti-GIP serum after oral glucose in rats.

B Lauritsen1, J J Holst, A J Moody.   

Abstract

An oral glucose tolerance test (OGTT), an OGTT after infusion of anti-gastric inhibitory polypeptide (GIP) serum, and an intravenous glucose infusion were performed in unrestrained and unanesthetized rats. In the rats treated with anti-GIP serum the insulin release was significantly depressed. This finding supports the concept that GIP is a physiologically important 'glucose-dependent insulin-releasing peptide'.

Entities:  

Mesh:

Substances:

Year:  1981        PMID: 16435485     DOI: 10.3109/00365528109181990

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  4 in total

Review 1.  New developments in the incretin concept.

Authors:  W Creutzfeldt; R Ebert
Journal:  Diabetologia       Date:  1985-08       Impact factor: 10.122

Review 2.  Incretins, insulin secretion and Type 2 diabetes mellitus.

Authors:  T Vilsbøll; J J Holst
Journal:  Diabetologia       Date:  2004-02-13       Impact factor: 10.122

3.  Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption.

Authors:  R Ebert; H Unger; W Creutzfeldt
Journal:  Diabetologia       Date:  1983-06       Impact factor: 10.122

4.  Effect of monoclonal antibodies to enteroglucagon on ileal adaptation after proximal small bowel resection.

Authors:  M Gregor; H Menge; R Stössel; E O Riecken
Journal:  Gut       Date:  1987       Impact factor: 23.059

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.