| Literature DB >> 16434708 |
Je Hee Lee1,2, Kyung Ho Han2, Seon Young Choi1,2, Marcelino E S Lucas3, C Mondlane4, M Ansaruzzaman5, G Balakrish Nair5, David A Sack5, Lorenz von Seidlein2, John D Clemens2, Manki Song2, Jongsik Chun1,2, Dong Wook Kim2.
Abstract
Vibrio cholerae O1 isolates belonging to the Ogawa serotype, El Tor biotype, harbouring the classical CTX prophage were first isolated in Mozambique in 2004. Multilocus sequence typing (MLST) analysis using nine genetic loci showed that the Mozambique isolates have the same sequence type (ST) as O1 El Tor N16961, a representative of the current seventh cholera pandemic. Analysis of the CTX prophage in the Mozambique isolates indicated that there is one type of rstR in these isolates: the classical CTX prophage. It was also found that the ctxB-rstR-rstA-rstB-phs-cep fragment was PCR-amplified from these isolates, which indicates the presence of a tandem repeat of the classical CTX prophage in the genome of the Mozambique isolates. The possible origin of these isolates and the presence of the tandem repeat of the classical prophage in them implicate the presence of the classical CTX phage.Entities:
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Year: 2006 PMID： 16434708 DOI： 10.1099/jmm.0.46287-0
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472