J A 'Chris' Delaney1, Lucie Opatrny, Samy Suissa. 1. Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Center, McGill University, Montreal, Canada.
Abstract
AIM: On the basis of a recent report, we assessed whether the use of warfarin by elderly drivers results in an increased risk of motor vehicle crash. METHODS: We used computerized records of Quebec insurance programmes, covering a population of 7 million people, to conduct a case-control study based on 5,579 cases and 12,911 controls. RESULTS: The rate of injurious motor vehicle crash associated with the use of warfarin in the past year was not elevated (rate ratio 0.74; 95% confidence interval 0.55, 1.05). CONCLUSIONS: Warfarin therapy does not appear to increase the risk of motor vehicle accidents in elderly drivers.
AIM: On the basis of a recent report, we assessed whether the use of warfarin by elderly drivers results in an increased risk of motor vehicle crash. METHODS: We used computerized records of Quebec insurance programmes, covering a population of 7 million people, to conduct a case-control study based on 5,579 cases and 12,911 controls. RESULTS: The rate of injurious motor vehicle crash associated with the use of warfarin in the past year was not elevated (rate ratio 0.74; 95% confidence interval 0.55, 1.05). CONCLUSIONS:Warfarin therapy does not appear to increase the risk of motor vehicle accidents in elderly drivers.
Authors: Ludivine Orriols; Louis-Rachid Salmi; Pierre Philip; Nicholas Moore; Bernard Delorme; Anne Castot; Emmanuel Lagarde Journal: Pharmacoepidemiol Drug Saf Date: 2009-08 Impact factor: 2.890
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