Literature DB >> 16433827

Preeclampsia: the death of Goliath.

Bruce B Feinberg1.   

Abstract

In this review, a novel and unifying pathophysiologic mechanism of preeclampsia is presented whereby a minimal excess of placental immune complex production versus removal causes a proinflammatory autoamplification cascade of trophoblast apoptosis/necrosis and oxidative stress, culminating in clinical preeclampsia. This concept immediately leads to a plethora of new and robust therapeutic strategies.

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Year:  2006        PMID： 16433827     DOI： 10.1111/j.1600-0897.2005.00362.x

Source DB:  PubMed          Journal:  Am J Reprod Immunol        ISSN： 1046-7408            Impact factor:   3.886


  8 in total

1.  Vital role of the calpain-calpastatin system for placental-integrity-dependent embryonic survival.

Authors:  Jiro Takano; Naomi Mihira; Ryo Fujioka; Emi Hosoki; Athar H Chishti; Takaomi C Saido
Journal:  Mol Cell Biol       Date:  2011-07-26       Impact factor: 4.272

2.  Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia.

Authors:  A Halmos; J Rigó; J Szijártó; G Füst; Z Prohászka; A Molvarec
Journal:  Clin Exp Immunol       Date:  2012-07       Impact factor: 4.330

3.  Nicotine inhibits cytokine production by placenta cells via NFkappaB: potential role in pregnancy-induced hypertension.

Authors:  Oonagh Dowling; Burton Rochelson; Kathleen Way; Yousef Al-Abed; Christine N Metz
Journal:  Mol Med       Date:  2007 Nov-Dec       Impact factor: 6.354

4.  Placental secretion of interleukin-1 and interleukin-1 receptor antagonist in preeclampsia: effect of magnesium sulfate.

Authors:  Alaa Amash; Gershon Holcberg; Olga Sapir; Mahmoud Huleihel
Journal:  J Interferon Cytokine Res       Date:  2012-08-21       Impact factor: 2.607

5.  Pregnancy-Associated Atypical Hemolytic Uremic Syndrome: A Systematic Review.

Authors:  Megha Gupta; Shravya Govindappagari; Richard M Burwick
Journal:  Obstet Gynecol       Date:  2020-01       Impact factor: 7.623

6.  DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia.

Authors:  Tingting Liao; Xia Xu; Xu Ye; Jianying Yan
Journal:  Sci Rep       Date:  2022-02-21       Impact factor: 4.379

7.  (31)P and (1)h nuclear magnetic resonance spectroscopy of blood plasma in female patients with preeclampsia.

Authors:  Susanne Schott; Josef Hahn; Christian Kurbacher; Detlef Moka
Journal:  Int J Biomed Sci       Date:  2012-12

8.  Screening preeclamptic cord plasma for proteins associated with decreased breast cancer susceptibility.

Authors:  Hoi Pang Low; Ashutosh Tiwari; Jagadeesh Janjanam; Li Qiu; Chien-I Chang; William C Strohsnitter; Errol R Norwitz; Sun W Tam; James E Evans; Karin M Green; Joao A Paulo; Mats Lambe; Chung-Cheng Hsieh
Journal:  Genomics Proteomics Bioinformatics       Date:  2013-12-05       Impact factor: 7.691
  8 in total

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