Literature DB >> 16432997

Tertiary syphilis presenting as hepatic bull's eye lesions.

L Peeters1, W Van Vaerenbergh, C Van der Perre, W Lagrange, M Verbeke.   

Abstract

We report a rare case of tertiary syphilis (hepatic gummata, asymptomatic neurosyphilis and iridocyclitis) in a 47 year old female patient. Our patient suffered from a troubled sight, pain in the right hypochondrium, one enlarged submandibular lymph node, an elevated sedimentation rate, disturbed liver tests and two hepatic lesions upon abdominal computed tomography. The diagnosis was based upon a liver biopsy and a positive Treponema Pallidum haemagglutination test. The patient was treated with doxycyclin. After treatment the sedimentation rate and liver tests normalised and the hepatic lesions disappeared leaving a small 'scar' on CT-scan; at the end she still complained of a decreased sight. We conclude that syphilitic gummata of the liver have a favourable prognosis when the diagnosis is made early. One has to differentiate with hepatic abscesses, primary tumours and metastases.

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Year:  2005        PMID: 16432997

Source DB:  PubMed          Journal:  Acta Gastroenterol Belg        ISSN: 1784-3227            Impact factor:   1.316


  2 in total

1.  Tertiary syphilis mimicking hepatic metastases of underlying primary peritoneal serous carcinoma.

Authors:  Hyun Jeong Shim
Journal:  World J Hepatol       Date:  2010-09-27

2.  Tertiary syphilis mimicking metastatic rectal cancer.

Authors:  Matthew J Smith; Meydene Ong; Abrar Maqbool
Journal:  J Surg Case Rep       Date:  2022-03-26
  2 in total

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