Literature DB >> 16432576

One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water.

Muhammad Abbas1, John Bethke, Ludger A Wessjohann.   

Abstract

Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.

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Year:  2005        PMID： 16432576     DOI： 10.1039/b514597j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Solid-phase synthesis of reduced selenocysteine tetrapeptides and their oxidized analogs containing selenenylsulfide eight-membered rings.

Authors:  Ludger A Wessjohann; Alex Schneider; Goran N Kaluđerović; Wolfgang Brandt
Journal:  Mol Divers       Date:  2013-06-01       Impact factor: 2.943

2.  One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates.

Authors:  Alexander F de la Torre; Akbar Ali; Fábio Z Galetto; Antonio L Braga; José A C Delgado; Márcio W Paixão
Journal:  Mol Divers       Date:  2019-02-18       Impact factor: 2.943

3.  Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles.

Authors:  Thimmalapura M Vishwanatha; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Alexander Dömling
Journal:  J Org Chem       Date:  2017-08-25       Impact factor: 4.354
  3 in total

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