Literature DB >> 16431340

Transcriptional repression of interleukin-2 in human systemic lupus erythematosus.

Christina G Katsiari1, George C Tsokos.   

Abstract

T cells from patients with SLE produce decreased amounts of interleukin-2 (IL-2), a central cytokine in the regulation of the immune response. We discuss herein the abnormalities underlying IL-2 deficiency in SLE T cells.

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Year:  2005        PMID： 16431340     DOI： 10.1016/j.autrev.2005.08.009

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  18 in total

1.  Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis.

Authors:  Jay Mehta; Anna Genin; Michael Brunner; Lisabeth V Scalzi; Nilamadhab Mishra; Timothy Beukelman; Randy Q Cron
Journal:  Arthritis Rheum       Date:  2010-08

2.  Estrogen upregulates cyclic AMP response element modulator α expression and downregulates interleukin-2 production by human T lymphocytes.

Authors:  Vaishali R Moulton; Dana R Holcomb; Melissa C Zajdel; George C Tsokos
Journal:  Mol Med       Date:  2012-05-09       Impact factor: 6.354

Review 3.  The contribution of interleukin-2 to effective wound healing.

Authors:  Karen M Doersch; Daniel J DelloStritto; M Karen Newell-Rogers
Journal:  Exp Biol Med (Maywood)       Date:  2016-10-25

4.  Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus.

Authors:  Lynda Mazari; Meryem Ouarzane; Moncef Zouali
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-02       Impact factor: 11.205

5.  cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.

Authors:  Christian M Hedrich; Jose C Crispin; Thomas Rauen; Christina Ioannidis; Sokratis A Apostolidis; Mindy S Lo; Vasileios C Kyttaris; George C Tsokos
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-26       Impact factor: 11.205

Review 6.  Estrogen receptor signaling and its relationship to cytokines in systemic lupus erythematosus.

Authors:  E Kassi; P Moutsatsou
Journal:  J Biomed Biotechnol       Date:  2010-06-10

7.  Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice.

Authors:  Wooki Kim; Yang-Yi Fan; Roger Smith; Bhimanagouda Patil; Guddadarangavvanahally K Jayaprakasha; David N McMurray; Robert S Chapkin
Journal:  J Nutr       Date:  2009-03-25       Impact factor: 4.798

8.  Stimulation of T cells up-regulates expression of Ifi202, an interferon-inducible lupus susceptibility gene, through activation of JNK/c-Jun pathway.

Authors:  Jianming Chen; Ravichandran Panchanathan; Divaker Choubey
Journal:  Immunol Lett       Date:  2008-03-13       Impact factor: 3.685

Review 9.  Novel molecular targets in the treatment of systemic lupus erythematosus.

Authors:  José C Crispín; George C Tsokos
Journal:  Autoimmun Rev       Date:  2007-12-04       Impact factor: 9.754

10.  Influence of interleukin-2 deficiency on the generation of autoimmune B cells.

Authors:  Lucile E Wrenshall; Deandra R Smith; Elliot T Stevens; John D Miller
Journal:  J Autoimmun       Date:  2007-08-09       Impact factor: 7.094
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