| Literature DB >> 16431116 |
Li Yang1, Lin-Hua Qin, S W Annie Bligh, A Bashall, Chao-Feng Zhang, Mian Zhang, Zheng-Tao Wang, Luo-Shan Xu.
Abstract
Investigation of phenolic patterns from the stems of Dendrobium chrysanthum by HPLC-PDA-MS has led to the isolation of a new phenanthrene derivative with a spirolactone ring, dendrochrysanene (1), that proved to suppress the mRNA level of TNF-alpha, IL8, IL10, and iNOS in murine peritoneal macrophages. The structure of 1 was characterized on the basis of various NMR (1H, 13C, 1H-1H COSY, HMQC, and HMBC), mass spectrometry, and X-ray crystal diffraction data.Entities:
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Year: 2006 PMID： 16431116 DOI： 10.1016/j.bmc.2006.01.004
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641