| Literature DB >> 16428796 |
H Martin Vordermeier1, Kris Huygen, Mahavir Singh, R Glyn Hewinson, Zhou Xing.
Abstract
Cattle were vaccinated with an adenovirus expressing the mycobacterial antigen 85A (rAd85A), with Mycobacterium bovis BCG followed by rAd85A heterologous boosting, or with rAd85A followed by BCG boosting. BCG/rAd85A resulted in the highest direct gamma interferon responses. Cultured enzyme-linked immunospot assay analysis demonstrated that memory responses were induced by all three protocols but were strongest after BCG/rAd85A and rAd85A/BCG vaccination.Entities:
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Year: 2006 PMID: 16428796 PMCID: PMC1360309 DOI: 10.1128/IAI.74.2.1416-1418.2006
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441