Literature DB >> 16428137

Effect of ionizing radiation on rat tissue: proteomic and biochemical analysis.

Eui-Chul Park1, Jong-Bok Yoon, Jin-Sil Seong, Kyoung-Soo Choi, Eung-Sik Kong, Yun-Jeong Kim, Young-Mee Park, Eun-Mi Park.   

Abstract

Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.

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Year:  2006        PMID： 16428137     DOI： 10.1080/10826060500388470

Source DB:  PubMed          Journal:  Prep Biochem Biotechnol        ISSN： 1082-6068            Impact factor:   2.162


  6 in total

1.  Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.

Authors:  Yeunhwa Gu; Chien-Sheng Huang; Tota Inoue; Takenori Yamashita; Torao Ishida; Ki-Mun Kang; Atsunori Nakao
Journal:  J Clin Biochem Nutr       Date:  2010-04-23       Impact factor: 3.114

2.  Protein lysine-Nζ alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species.

Authors:  Nigam Kumar; Hans Ippel; Christian Weber; Tilman Hackeng; Kevin H Mayo
Journal:  Protein Sci       Date:  2013-01-27       Impact factor: 6.725

3.  A systematic proteomic study of irradiated DNA repair deficient Nbn-mice.

Authors:  Anna Melchers; Lars Stöckl; Janina Radszewski; Marco Anders; Harald Krenzlin; Candy Kalischke; Regina Scholz; Andreas Jordan; Grit Nebrich; Joachim Klose; Karl Sperling; Martin Digweed; Ilja Demuth
Journal:  PLoS One       Date:  2009-05-01       Impact factor: 3.240

Review 4.  Chernobyl seed project. Advances in the identification of differentially abundant proteins in a radio-contaminated environment.

Authors:  Namik M Rashydov; Martin Hajduch
Journal:  Front Plant Sci       Date:  2015-07-06       Impact factor: 5.753

5.  Do Cupins Have a Function Beyond Being Seed Storage Proteins?

Authors:  Daša Gábrišová; Katarína Klubicová; Maksym Danchenko; Dušan Gömöry; Valentyna V Berezhna; Ludovit Skultety; Ján A Miernyk; Namik Rashydov; Martin Hajduch
Journal:  Front Plant Sci       Date:  2016-01-13       Impact factor: 5.753

6.  Effects of Acanthopanax senticosus on Brain Injury Induced by Simulated Spatial Radiation in Mouse Model Based on Pharmacokinetics and Comparative Proteomics.

Authors:  Yingyu Zhou; Cuilin Cheng; Denis Baranenko; Jiaping Wang; Yongzhi Li; Weihong Lu
Journal:  Int J Mol Sci       Date:  2018-01-15       Impact factor: 5.923
  6 in total

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