Literature DB >> 16427709

Gene transcription in trypanosomes.

Jennifer B Palenchar1, Vivian Bellofatto.   

Abstract

Trypanosoma brucei and the other members of the trypanosomatid family of parasitic protozoa, contain an unusual RNA polymerase II enzyme, uncoordinated mRNA 5' capping and transcription initiation events, and most likely contain an abridged set of transcription factors. Pre-mRNA start sites remain elusive. In addition, two important life cycle stage-specific mRNAs are transcribed by RNA polymerase I. This review interprets these unusual transcription traits in the context of parasite biology.

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Year:  2006        PMID： 16427709     DOI： 10.1016/j.molbiopara.2005.12.008

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  69 in total

1.  Diversification of function by different isoforms of conventionally shared RNA polymerase subunits.

Authors:  Sara Devaux; Steven Kelly; Laurence Lecordier; Bill Wickstead; David Perez-Morga; Etienne Pays; Luc Vanhamme; Keith Gull
Journal:  Mol Biol Cell       Date:  2007-01-31       Impact factor: 4.138

2.  mRNA maturation by two-step trans-splicing/polyadenylation processing in trypanosomes.

Authors:  Adriana V Jäger; Javier G De Gaudenzi; Alejandro Cassola; Iván D'Orso; Alberto C Frasch
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-31       Impact factor: 11.205

3.  RNA polymerase transcription machinery in trypanosomes.

Authors:  Anish Das; Mahrukh Banday; Vivian Bellofatto
Journal:  Eukaryot Cell       Date:  2007-10-19

4.  CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei.

Authors:  Michael D Scahill; Irena Pastar; George A M Cross
Journal:  Mol Biochem Parasitol       Date:  2007-10-06       Impact factor: 1.759

5.  Characterization and localization of a hybrid non-ribosomal peptide synthetase and polyketide synthase gene from the toxic dinoflagellate Karenia brevis.

Authors:  Susanna López-Legentil; Bongkeun Song; Michael DeTure; Daniel G Baden
Journal:  Mar Biotechnol (NY)       Date:  2009-05-27       Impact factor: 3.619

6.  Structure of the C-terminal domain of transcription factor IIB from Trypanosoma brucei.

Authors:  B Syed Ibrahim; Nalini Kanneganti; Gabrielle E Rieckhof; Anish Das; Douglas V Laurents; Jennifer B Palenchar; Vivian Bellofatto; David A Wah
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-03       Impact factor: 11.205

Review 7.  Epigenetic regulation in African trypanosomes: a new kid on the block.

Authors:  Luisa M Figueiredo; George A M Cross; Christian J Janzen
Journal:  Nat Rev Microbiol       Date:  2009-07       Impact factor: 60.633

8.  Identification and characterization of nuclear non-canonical poly(A) polymerases from Trypanosoma brucei.

Authors:  Ronald D Etheridge; Daniel M Clemens; Paul D Gershon; Ruslan Aphasizhev
Journal:  Mol Biochem Parasitol       Date:  2008-11-25       Impact factor: 1.759

9.  TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.

Authors:  Hee-Sook Kim; George A M Cross
Journal:  PLoS Pathog       Date:  2010-07-08       Impact factor: 6.823

10.  tRNASec is transcribed by RNA polymerase II in Trypanosoma brucei but not in humans.

Authors:  Eric Aeby; Elisabetta Ullu; Hasmik Yepiskoposyan; Bernd Schimanski; Isabel Roditi; Oliver Mühlemann; André Schneider
Journal:  Nucleic Acids Res       Date:  2010-05-05       Impact factor: 16.971
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