OBJECTIVE: We evaluated the effect of a micronutrient-fortified beverage on mental function in schoolchildren. METHODS: This double-blind, placebo-controlled, matched-pair, cluster, randomized feeding trial assessed baseline before supplementation and after 14 mo in a cohort of 608 children aged 6 to 15 y who received amicronutrient-fortified beverage or placebo. Children in two classes (clusters) in each of nine grades were assessed for intelligence, attention and concentration, memory, and school achievement. RESULTS:Mean intelligence quotient scores of the micronutrient-fortified beverage group and the placebo group at baseline and final follow-up were not significantly different. Mean verbal and performance scores and increments were also not different. After supplementation, attention-concentration increment scores of the micronutrient group were significantly higher (P < 0.05) than those of the placebo group. Mean and incremental scores of the supplemented group on the memory scale were not significantly different from those of the placebo group. CONCLUSIONS: Supplementation with a beverage fortified with a range of micronutrients significantly improved attention-concentration over 14 mo, but not intelligence quotient, memory, or school achievement among middle-income schoolchildren.
RCT Entities:
OBJECTIVE: We evaluated the effect of a micronutrient-fortified beverage on mental function in schoolchildren. METHODS: This double-blind, placebo-controlled, matched-pair, cluster, randomized feeding trial assessed baseline before supplementation and after 14 mo in a cohort of 608 children aged 6 to 15 y who received a micronutrient-fortified beverage or placebo. Children in two classes (clusters) in each of nine grades were assessed for intelligence, attention and concentration, memory, and school achievement. RESULTS: Mean intelligence quotient scores of the micronutrient-fortified beverage group and the placebo group at baseline and final follow-up were not significantly different. Mean verbal and performance scores and increments were also not different. After supplementation, attention-concentration increment scores of the micronutrient group were significantly higher (P < 0.05) than those of the placebo group. Mean and incremental scores of the supplemented group on the memory scale were not significantly different from those of the placebo group. CONCLUSIONS: Supplementation with a beverage fortified with a range of micronutrients significantly improved attention-concentration over 14 mo, but not intelligence quotient, memory, or school achievement among middle-income schoolchildren.
Authors: Tora Mitra-Ganguli; Soumik Kalita; Sakshi Bhushan; Con Stough; James Kean; Nan Wang; Vidhu Sethi; Anuradha Khadilkar Journal: Front Pharmacol Date: 2017-11-17 Impact factor: 5.810
Authors: Aldo A M Lima; Michelle P Kvalsund; Paula P E de Souza; Ítalo L Figueiredo; Alberto M Soares; Rosa M S Mota; Noélia L Lima; Relana C Pinkerton; Peter P Patrick; Richard L Guerrant; Reinaldo B Oriá Journal: Clinics (Sao Paulo) Date: 2013 Impact factor: 2.365