Literature DB >> 16421344

Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans.

Edward L Melanson1, William T Donahoo, Fran Dong, Therese Ida, Michael B Zemel.   

Abstract

OBJECTIVE: Higher calcium and dairy intakes may be associated with lower body weights, but a mechanism in humans has yet to be elucidated. We compared the effects of a dairy-based high-calcium diet and a low-calcium diet on macronutrient oxidation. RESEARCH METHODS AND PROCEDURES: Subjects (10 men and nine women) consumed a low-dairy (LD, approximately one serving per day, approximately 500 mg Ca(2+)/d) or high-dairy (HD, approximately three to four servings per day, approximately 1400 mg Ca(2+)/d) energy balance diet for 1 week. Each diet condition was performed twice. On the 7th day, subjects were studied in a room calorimeter under one of four study conditions, applied in a randomized crossover design. Within each diet condition, subjects were studied under conditions of energy balance and acute energy deficit. The deficit (-600 kcal/d) was induced only for the 24 hours that subjects resided in the room and was achieved by a combination of caloric restriction and exercise.
RESULTS: Under energy balance conditions, there was no effect of diet treatment on respiratory quotient or 24-hour macronutrient oxidation. Under energy deficit conditions, 24-hour fat oxidation was significantly increased on the HD diet (HD with deficit = 136 +/- 13 g/d, LD with deficit = 106 +/- 7 g/d, p = 0.02). DISCUSSION: Consumption of a dairy-based high-calcium diet increased 24-hour fat oxidation under conditions of acute energy deficit. We hypothesize that these effects are due to an increased fat oxidation during exercise.

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Year:  2005        PMID: 16421344     DOI: 10.1038/oby.2005.261

Source DB:  PubMed          Journal:  Obes Res        ISSN: 1071-7323


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