Literature DB >> 16419616

Proteomics: a paradigm shift.

Anu Kalia1, R P Gupta.   

Abstract

Proteome--the protein complement of a genome--has become the protein renaissance and a key research tool in the post-genomic era. The basic technology involves the routine usage of gel electrophoresis and spectrometry procedures for deciphering the primary protein sequence/structure as well as knowing certain unique post-translational modifications that a particular protein has undergone to perform a specific function in the cell. However, the recent advancements in protein analysis have ushered this science to provide deeper, bigger and more valuable perspectives regarding performance of subtle protein-protein interactions. Applications of this branch of molecular biology are as vast as the subject is and include clinical diagnostics, pharmaceutical and biotechnological industries. The 21st century hails the use of products, procedures and advancements of this science as finer touches required for the grooming of fast-paced technology.

Mesh:

Year:  2005        PMID: 16419616     DOI: 10.1080/07388550500365102

Source DB:  PubMed          Journal:  Crit Rev Biotechnol        ISSN: 0738-8551            Impact factor:   8.429


  2 in total

Review 1.  Two-dimensional gel electrophoresis in bacterial proteomics.

Authors:  Shirly O T Curreem; Rory M Watt; Susanna K P Lau; Patrick C Y Woo
Journal:  Protein Cell       Date:  2012-05-18       Impact factor: 14.870

2.  Comparative proteomic analysis of kidney development-related proteins in the pig.

Authors:  Young-Joo Jeon; Jumi Kim; Jung-Il Chae
Journal:  In Vitro Cell Dev Biol Anim       Date:  2013-04-13       Impact factor: 2.416

  2 in total

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