Literature DB >> 16417786

Extracts of Monascusus purpureus beyond statins--profile of efficacy and safety of the use of extracts of Monascus purpureus.

Antonio Bianchi1.   

Abstract

Extracts of Monascus purpureus have always been considered a natural source of lovastatin, the precursor of the world's largest selling class of drugs. In actual fact, the fungus contains many other substances (flavonoids, polyunsaturated fats, pyrrolinic compounds etc.) with a wide variety of other actions. The most recent studies have shown that it has an action on the glycemic metabolism, and on the mechanisms of adipogenesis, also an effects on the endothelium and on postprandial vasodilation. These effects are more extensive and complex than those of statins alone. And new strains of Monascus purpureus have recently been patented where the presence of statins is only one of the therapeutic components of the fungus. In particular, the increase in secondary components, such as flavonoids, which coincides with a more complex therapeutic action, probably making the new extracts of Monascus purpureus, the ideal candidate for the treatment of the metabolic syndrome.

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Year:  2005        PMID: 16417786     DOI: 10.1007/bf02835797

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  30 in total

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6.  Effects of xuezhikang, an extract of cholestin, on lipid profile and C-reactive protein: a short-term time course study in patients with stable angina.

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Journal:  Circulation       Date:  1997-10-21       Impact factor: 29.690

9.  Xuezhikang decreases serum lipoprotein(a) and C-reactive protein concentrations in patients with coronary heart disease.

Authors:  Ling Liu; Shui-Ping Zhao; Yan-Chun Cheng; Yu-Ling Li
Journal:  Clin Chem       Date:  2003-08       Impact factor: 8.327

10.  Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment.

Authors:  Antoniom Ceriello; Lisa Quagliaro; Ludovica Piconi; Roberta Assaloni; Roberto Da Ros; Amabile Maier; Katherine Esposito; Dario Giugliano
Journal:  Diabetes       Date:  2004-03       Impact factor: 9.461

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  2 in total

Review 1.  Monascus secondary metabolites: production and biological activity.

Authors:  Petra Patakova
Journal:  J Ind Microbiol Biotechnol       Date:  2012-11-20       Impact factor: 3.346

2.  Effect of a Monascus sp. Red Yeast Rice Extract on Germination of Bacterial Spores.

Authors:  Marketa Husakova; Michaela Plechata; Barbora Branska; Petra Patakova
Journal:  Front Microbiol       Date:  2021-05-24       Impact factor: 5.640

  2 in total

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