| Literature DB >> 16416123 |
August Stich1, Nadja Oster, Inas Z Abdel-Aziz, Gabriele Stieglbauer, Boubacar Coulibaly, Hannes Wickert, Jeremy McLean, Bocar A Kouyaté, Heiko Becher, Michael Lanzer.
Abstract
A malaria survey of the entire population of a village in Western Burkina Faso (n=1,561) was conducted to assess malaria endemicity. The study population was examined for symptoms characteristic of malaria including fever, anaemia, splenomegaly and parasites present in thick blood films. In the overall study population, the prevalence of Plasmodium spp. infection by microscopic examination of thick blood films was 79.0% (1,233/1,561). In a subcohort with 201 individuals, PCR techniques found a prevalence rate for all Plasmodium spp. of 92.0% (185/201), while microscopy found one of 80.6% (162/201). A combination of both methods gives a rate of 95.5% (192/201). Though univariate logistic analyses of elevated body temperature, anaemia, splenomegaly and age showed them all to be predictors of or risk factors for an infection, only elevated body temperature and age were predictors in multivariate logistic analysis. However, the symptom of splenomegaly did show a highly significant association with infection by multiple species of Plasmodium.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16416123 DOI： 10.1007/s00436-005-0104-9
Source DB: PubMed Journal: Parasitol Res ISSN： 0932-0113 Impact factor: 2.289