Diabetic hyperosmolarity: a consequence of loss of autonomy.

Diabetic hyperosmolarity is a serious acute metabolic disorder mainly occurring in the frail elderly subject presenting age-related favoring factors (reduced sensation of thirst, altered endocrine regulation), disease-related favoring factors (cognitive impairment, poor nutritional status and/or loss of autonomy), and a triggering factor, generally infection. Diabetic hyperosmolarity can occur in a previously non-diabetic patient. Intense dehydration dominants the clinical picture. The prognosis depends largely on the underlying chronic disease.