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Literature DB >> 16414830

Role of quinone moiety as antitumour agents: a review.

Z S Saify¹, N Mushtaq, F Noor, S Takween, M Arif.

Abstract

Quinone antitumour agents with wide spectrum of activity have been extensively used in different forms of human cancers. Quinones have been isolated either from animals, microorganisms or plants. Extensive research on quinone compounds is going on to discover novel effective antitumour compound. We also discussed the mechanism of action, which have not been fully clarified. In this review we cover all the above-mentioned aspects to emphasize the importance of quinone moiety as antitumour agents.

Entities: Chemical Disease Species

Year: 1999 PMID： 16414830

Source DB: PubMed Journal: Pak J Pharm Sci ISSN： 1011-601X Impact factor: 0.684

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Cited

5 in total

Role of quinone moiety as antitumour agents: a review.

1. Design and synthesis of novel isoxazole tethered quinone-amino Acid hybrids.

2. Anthraquinone G503 induces apoptosis in gastric cancer cells through the mitochondrial pathway.

3. Antibacterial Activity of Juglone against Staphylococcus aureus: From Apparent to Proteomic.

4. Cytotoxic and antiproliferative effects of thymoquinone on rat C6 glioma cells depend on oxidative stress.

5. Antiproliferative activity of the isofuranonaphthoquinone isolated from Bulbine frutescens against Jurkat T cells.