Acetylation percentage method for determination of acetylator status in human volunteers and tuberculous patients.

Acetylation percentage method described here is rapid and economical. A comparison has been made between plasma half life (t (1/2)), acetylation ratio and acetylation percentage methods for the determination of phenotyping. Isoniazid (INH) was selected as a test drug. In 120 healthy volunteers and 60 tuberculosis patients, acetylation percentage method has been found simple and reliable as compared to the other methods.