Literature DB >> 16414756

Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis.

Y F Kazi1, R Parton, B A Memon.   

Abstract

The aim of this study was to device a simple, sensitive and convenient assay for the detection of toxicity of the Adenylate cyclase toxin (ACT), a newly recognized toxin of Bordetella pertussis. Haemolytic activity of ACT was analysed as an assay and sheep RBCs were found to be suitable to detect the toxic effect down to the dose of 6.25 nmol cAMP/min/ml enzymic activity applied. The haemolytic activity was found to be dose-dependent.

Entities:  

Year:  1994        PMID： 16414756

Source DB:  PubMed          Journal:  Pak J Pharm Sci        ISSN： 1011-601X            Impact factor:   0.684


  4 in total

1.  Evaluation of selected antitumor agents as subversive substrate and potential inhibitor of trypanothione reductase: an alternative approach for chemotherapy of Leishmaniasis.

Authors:  Anil Kumar Shukla; Sanjukta Patra; Vikash Kumar Dubey
Journal:  Mol Cell Biochem       Date:  2011-02-26       Impact factor: 3.396

2.  Exploration of antiplasmodial activity in Acalypha wilkesiana Müller Argoviensis, 1866 (family: Euphorbiaceae) and its GC-MS fingerprint.

Authors:  Wandayi Emmanuel Amlabu; Ishaya Haruna Nock; Naveen Kumar Kaushik; Dinesh Mohanakrishnan; Jyoti Tiwary; Patrick Ahmadu Audu; Musbahu S Abubakar; Dinkar Sahal
Journal:  Parasitol Res       Date:  2018-03-17       Impact factor: 2.289

3.  Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani.

Authors:  Wandayi Emmanuel Amlabu; Christine Achiaa Antwi; Gordon Awandare; Theresa Manful Gwira
Journal:  PLoS Negl Trop Dis       Date:  2020-04-10

4.  Some novel antileishmanial compounds inhibit normal cell cycle progression of Leishmania donovani promastigotes and exhibits pro-oxidative potential.

Authors:  Wandayi Emmanuel Amlabu; Cynthia Mmalebna Amisigo; Christine Achiaa Antwi; Gordon Akanzuwine Awandare; Theresa Manful Gwira
Journal:  PLoS One       Date:  2021-11-22       Impact factor: 3.240
  4 in total

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