Literature DB >> 16414591

Application of Limulus Amebocyte Lysate (LAL) test for detecting endotoxin (pyrogen) in large volume parenterals.

S Baqir Naqvi1, Tariq Mirza, Dilnawaz Sheikh, Tanveer Abbas.   

Abstract

Screening of twenty five large volume parenterals including dextrose, electrolytes, mannitol, metronidazole infusions, haemodialysis solution, water for injections and distilled water for the determination of pyrogen using Limulus Amebocyte Lysate (LAL) test has been carried out. Out of different preparations only one metronidazole injection exhibited positive LAL test, which was found pyrogen free with USP rabbit pyrogen test.

Entities:  

Year:  2004        PMID： 16414591

Source DB:  PubMed          Journal:  Pak J Pharm Sci        ISSN： 1011-601X            Impact factor:   0.684


  3 in total

1.  Systemic endotoxin levels in chronic indolent periodontal infections.

Authors:  J L Ebersole; J Stevens; M J Steffen; D Dawson Iii; M J Novak
Journal:  J Periodontal Res       Date:  2010-02       Impact factor: 4.419

2.  Single Application of Low-Dose, Hydroxyapatite-Bound BMP-2 or GDF-5 Induces Long-Term Bone Formation and Biomechanical Stabilization of a Bone Defect in a Senile Sheep Lumbar Osteopenia Model.

Authors:  Ines Hasenbein; André Sachse; Peter Hortschansky; Klaus D Schmuck; Victoria Horbert; Christoph Anders; Thomas Lehmann; René Huber; Alexander Maslaris; Frank Layher; Christina Braun; Andreas Roth; Frank Plöger; Raimund W Kinne
Journal:  Biomedicines       Date:  2022-02-21

3.  The monocyte activation test detects potentiated cytokine release resulting from the synergistic effect of endotoxin and non-endotoxin pyrogens.

Authors:  Shabnam Solati; Ting Zhang; Shahrzad Timman
Journal:  Innate Immun       Date:  2022-05-02       Impact factor: 2.951
  3 in total

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