OBJECTIVE: To compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children. METHODS:Forty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n=16) received bupivacaine, group 2 (n=15) received ropivacaine, and a group 3 (control) (n=15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24h postoperatively. RESULTS: No difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p>0.05). The pain scores in both analgesia groups were significantly (p<0.05) lower 1, 4, 12, 16, and 24h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p<0.05) different between the analgesia and control groups. CONCLUSION:Local ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain.
RCT Entities:
OBJECTIVE: To compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children. METHODS: Forty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n=16) received bupivacaine, group 2 (n=15) received ropivacaine, and a group 3 (control) (n=15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24h postoperatively. RESULTS: No difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p>0.05). The pain scores in both analgesia groups were significantly (p<0.05) lower 1, 4, 12, 16, and 24h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p<0.05) different between the analgesia and control groups. CONCLUSION: Local ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain.
Authors: Gaia Georgopoulos; Patrick Carry; Zhaoxing Pan; Frank Chang; Travis Heare; Jason Rhodes; Mark Hotchkiss; Nancy H Miller; Mark Erickson Journal: J Bone Joint Surg Am Date: 2012-09-19 Impact factor: 5.284
Authors: Klaus Stelter; John Martin Hempel; Alexander Berghaus; Michaela Andratschke; Christian W Luebbers; Hjalmar Hagedorn Journal: Eur Arch Otorhinolaryngol Date: 2009-01-22 Impact factor: 2.503