| Literature DB >> 16413703 |
Peter T J Willemsen1, José Westerveen, Annemieke Dinkla, Douwe Bakker, Fred G van Zijderveld, Jelle E R Thole.
Abstract
We here describe the identification and characterization of three novel secreted Mycobacterium avium subsp. paratuberculosis antigens of 9, 15 and 34 kDa (Map2609, Map2942c and Map0210c, respectively) by screening a genomic expression library with a serum of a naturally infected clinical cow. The 9, 15 and 34 kDa antigens display strong homology to previously described M. tuberculosis antigens, TB8.4, MPT53 and Erp, respectively. Furthermore, these antigens were shown to be recognized by antibodies from infected cattle, when tested with a limited number of sera from subclinical (n=7) and clinical (n=3) infected cattle.Entities:
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Year: 2006 PMID： 16413703 DOI： 10.1016/j.vetmic.2005.12.005
Source DB: PubMed Journal: Vet Microbiol ISSN： 0378-1135 Impact factor: 3.293