| Literature DB >> 16413537 |
Frederica L Theodoulou1, Michael Holdsworth, Alison Baker.
Abstract
Peroxisomes perform a range of different functions, dependent upon organism, tissue type, developmental stage or environmental conditions, many of which are connected with lipid metabolism. This review summarises recent research on ATP binding cassette (ABC) transporters of the peroxisomal membrane (ABC subfamily D) and their roles in plants, fungi and animals. Analysis of mutants has revealed that peroxisomal ABC transporters play key roles in specific metabolic and developmental functions in different organisms. A common function is import of substrates for beta-oxidation but much remains to be determined concerning transport substrates and mechanisms which appear to differ significantly between phyla.Entities:
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Year: 2006 PMID: 16413537 DOI: 10.1016/j.febslet.2005.12.095
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124