Literature DB >> 16413494

Polyplex-embedding in polyelectrolyte multilayers for gene delivery.

Florent Meyer1, Vincent Ball, Pierre Schaaf, Jean Claude Voegel, Joelle Ogier.   

Abstract

In this work, incorporation of plasmid DNA, pre-complexed with PEI, into polyelectrolyte multilayers has been studied to further develop platforms for local gene delivery. Polyplex embedding in synthetic and naturally degradable architectures was efficient for transfection of human hepato-cellular carcinoma cells.

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Year:  2005        PMID： 16413494     DOI： 10.1016/j.bbamem.2005.11.015

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios.

Authors:  Sumit Mehrotra; Ilsoon Lee; Christina Chan
Journal:  Acta Biomater       Date:  2009-01-19       Impact factor: 8.947

2.  Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films.

Authors:  Maria Dimitrova; Christine Affolter; Florent Meyer; Isabelle Nguyen; Doriane G Richard; Catherine Schuster; Ralf Bartenschlager; Jean-Claude Voegel; Joëlle Ogier; Thomas F Baumert
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-15       Impact factor: 11.205

Review 3.  p53 gene in treatment of hepatic carcinoma: status quo.

Authors:  Yong-Song Guan; Zi La; Lin Yang; Qing He; Ping Li
Journal:  World J Gastroenterol       Date:  2007-02-21       Impact factor: 5.742

4.  Small-interfering RNA-eluting surfaces as a novel concept for intravascular local gene silencing.

Authors:  Andrea Nolte; Tobias Walker; Martina Schneider; Oya Kray; Meltem Avci-Adali; Gerhard Ziemer; Hans Peter Wendel
Journal:  Mol Med       Date:  2011-07-22       Impact factor: 6.354

5.  Delivery of plasmid DNA to vascular tissue in vivo using catheter balloons coated with polyelectrolyte multilayers.

Authors:  Eric M Saurer; Dai Yamanouchi; Bo Liu; David M Lynn
Journal:  Biomaterials       Date:  2010-10-08       Impact factor: 12.479

6.  Characterization of degradable polyelectrolyte multilayers fabricated using DNA and a fluorescently-labeled poly(β-amino ester): shedding light on the role of the cationic polymer in promoting surface-mediated gene delivery.

Authors:  Shane L Bechler; David M Lynn
Journal:  Biomacromolecules       Date:  2012-01-06       Impact factor: 6.988

7.  DNA release dynamics from bioreducible layer-by-layer films.

Authors:  Jenifer Blacklock; Guangzhao Mao; David Oupický; Helmuth Möhwald
Journal:  Langmuir       Date:  2010-06-01       Impact factor: 3.882

8.  Surface-Mediated Delivery of DNA: Cationic Polymers Take Charge.

Authors:  Christopher M Jewell; David M Lynn
Journal:  Curr Opin Colloid Interface Sci       Date:  2008-12       Impact factor: 6.448

9.  Multilayered Films Fabricated from Combinations of Degradable Polyamines: Tunable Erosion and Release of Anionic Polyelectrolytes.

Authors:  Jingtao Zhang; David M Lynn
Journal:  Macromolecules       Date:  2006-01-26       Impact factor: 5.985

Review 10.  Multilayered polyelectrolyte assemblies as platforms for the delivery of DNA and other nucleic acid-based therapeutics.

Authors:  Christopher M Jewell; David M Lynn
Journal:  Adv Drug Deliv Rev       Date:  2008-03-04       Impact factor: 15.470
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