Literature DB >> 16413450

Pain, malingering and the WAIS-III Working Memory Index.

Joseph L Etherton1, Kevin J Bianchini, Megan A Ciota, Matthew T Heinly, Kevin W Greve.   

Abstract

BACKGROUND CONTEXT: Pain patients often report cognitive symptoms, and many will include them in their claims of disability. There is empirical evidence that patients with pain do experience problems on attention-demanding cognitive tasks, but the results are mixed and the potential impact of exaggeration in the context of pain-related litigation has not been addressed.
PURPOSE: 1) Examine the impact of pain and malingering on attention; 2) determine if the Working Memory Index (WMI) of the Wechsler Adult Intelligence Scale-3 (WAIS-III) can reliably detect malingering. STUDY DESIGN/
SETTING: Study 1: simulator design; Study 2: clinical known-groups design. PATIENT SAMPLE: Study 1 used healthy college students; Study 2 used chronic pain patients and neurological patients. OUTCOME MEASURES: The WMI and its constituent subtests.
METHODS: Study 1: College students were administered the WMI under three conditions: standard administration, with cold-pressor induced pain, or with instructions to simulate impairment due to pain. Study 2: Known-groups design in which the WMI was examined in non-malingering and definite malingering chronic pain patients, non-malingering moderate-severe traumatic brain injury, and memory disorder patients seen for routine psychological evaluation. Malingering was operationalized using published criteria.
RESULTS: There were no group differences in WMI or its subtests among non-malingering groups, but some individual clinical patients with pain did score at a level suggestive of attentional impairment. The lowest scores were found in the simulated malingering college students and definite malingering clinical pain groups, in which about half scored worse than 95% of the non-malingering clinical patients.
CONCLUSIONS: This study demonstrated that even when controlling for exaggeration some pain patients do exhibit problems with attentional function. However, significant impairment in WMI performance (eg, index score<or=70), particularly in the absence of brain dysfunction, cannot reasonably be attributed to the effects of either acute or chronic pain, even at moderate to severe levels, and likely reflects intentional exaggeration.

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Year:  2006        PMID: 16413450     DOI: 10.1016/j.spinee.2005.05.382

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  7 in total

1.  Peripheral nerve injury leads to working memory deficits and dysfunction of the hippocampus by upregulation of TNF-α in rodents.

Authors:  Wen-Jie Ren; Yong Liu; Li-Jun Zhou; Wei Li; Yi Zhong; Rui-Ping Pang; Wen-Jun Xin; Xu-Hong Wei; Jun Wang; He-Quan Zhu; Chang-You Wu; Zhi-Hai Qin; Guosong Liu; Xian-Guo Liu
Journal:  Neuropsychopharmacology       Date:  2011-02-02       Impact factor: 7.853

2.  Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2.

Authors:  Jonathan Nissenbaum; Marshall Devor; Ze'ev Seltzer; Mathias Gebauer; Martin Michaelis; Michael Tal; Ruslan Dorfman; Merav Abitbul-Yarkoni; Yan Lu; Tina Elahipanah; Sonia delCanho; Anne Minert; Kaj Fried; Anna-Karin Persson; Hagai Shpigler; Erez Shabo; Benjamin Yakir; Anne Pisanté; Ariel Darvasi
Journal:  Genome Res       Date:  2010-08-05       Impact factor: 9.043

3.  Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents.

Authors:  Wen-Shan Gui; Xiao Wei; Chun-Lin Mai; Madhuvika Murugan; Long-Jun Wu; Wen-Jun Xin; Li-Jun Zhou; Xian-Guo Liu
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4.  CXCL12-mediated monocyte transmigration into brain perivascular space leads to neuroinflammation and memory deficit in neuropathic pain.

Authors:  Chun-Lin Mai; Zhi Tan; Ya-Nan Xu; Jing-Jun Zhang; Zhen-Hua Huang; Dong Wang; Hui Zhang; Wen-Shan Gui; Jun Zhang; Zhen-Jia Lin; Ying-Tong Meng; Xiao Wei; Ying-Tao Jie; Peter M Grace; Long-Jun Wu; Li-Jun Zhou; Xian-Guo Liu
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5.  Mid-term improvement of cognitive performance after total hip arthroplasty in patients with osteoarthritis of the hip : a prospective cohort study.

Authors:  André Strahl; Murteza Ali Kazim; Nils Kattwinkel; Wiebke Hauskeller; Steffen Moritz; Sönke Arlt; Andreas Niemeier
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Review 6.  Normalization of Neuroinflammation: A New Strategy for Treatment of Persistent Pain and Memory/Emotional Deficits in Chronic Pain.

Authors:  Xian-Guo Liu
Journal:  J Inflamm Res       Date:  2022-09-09

7.  Neurocognitive Changes after Sustained Ketamine Administration in Children with Chronic Pain.

Authors:  Amy Lee Bredlau; Brian T Harel; Michael P McDermott; Robert H Dworkin; David N Korones; James G Dolan; Heather R Adams
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  7 in total

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