Literature DB >> 16413431

To anticoagulate or not to anticoagulate? A common dilemma for the provider: physicians' opinion poll based on a case study of an older long-term care facility resident with dementia and atrial fibrillation.

T S Dharmarajan1, Surendran Varma, Shailaja Akkaladevi, Anna S Lebelt, Edward P Norkus.   

Abstract

OBJECTIVE: Anticoagulation therapy is an acceptable strategy for the prevention of thromboembolic events in the presence of atrial fibrillation. However, this strategy is controversial in older subjects particularly in the presence of dementia. We conducted an opinion poll regarding the decision to anticoagulate or not among physicians in practice and in various levels of training (residents and fellows) that was based on a specific, yet not unusual, case scenario in the nursing home.
SETTING: A university teaching hospital in the Bronx, NY.
METHODS: A survey questionnaire was distributed to physicians to solicit opinions on the decision to anticoagulate based on an actual case from a LTCF and the results were analyzed.
RESULTS: One hundred seven completed surveys were returned from 49 residents, 20 fellows, and 38 attending physicians. The majority (85%) felt that long-term anticoagulation therapy was not indicated in the case patient. However, most (88%) felt they would provide an antiplatelet agent, with the choice being 78% aspirin, 20% clopridogel, and 2% aspirin-dipyridamole. The most cited reasons for not providing anticoagulation were risk of falls (98%), dementia (40%), and short life expectancy (32%). However, 92% of respondents felt that the patient was a candidate for short-term anticoagulation therapy. Interestingly, the choices (yes, no, uncertain) to the questions were similar for all physicians irrespective of their level of training or years in practice (or faculty) after training.
CONCLUSIONS: Although long-term anticoagulation for thromboembolic events in atrial fibrillation is considered beneficial, recent reports suggest that warfarin is underused in older adults, especially in the long-term care setting. Our physician poll, based on a specific case scenario, is consistent with this opinion as reflected by both trainees and practicing physicians. While there are absolute and relative contraindications to the use of long-term warfarin, decisions should be individualized and based on risks, benefits, and quality of life of the resident.

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Year:  2005        PMID: 16413431     DOI: 10.1016/j.jamda.2005.08.002

Source DB:  PubMed          Journal:  J Am Med Dir Assoc        ISSN: 1525-8610            Impact factor:   4.669


  9 in total

1.  The effect of cognitive impairment in the elderly on the initial and long-term stability of warfarin therapy.

Authors:  Hanan S Khreizat; Peter Whittaker; Kristy D Curtis; Gerald Turlo; Candice L Garwood
Journal:  Drugs Aging       Date:  2012-04-01       Impact factor: 3.923

2.  Incidence and Determinants of Traumatic Intracranial Bleeding Among Older Veterans Receiving Warfarin for Atrial Fibrillation.

Authors:  John A Dodson; Andrew Petrone; David R Gagnon; Mary E Tinetti; Harlan M Krumholz; J Michael Gaziano
Journal:  JAMA Cardiol       Date:  2016-04-01       Impact factor: 14.676

3.  Barriers to a software reminder system for risk assessment of stroke in atrial fibrillation: a process evaluation of a cluster randomised trial in general practice.

Authors:  Tim A Holt; Andrew Rh Dalton; Susan Kirkpatrick; Jenny Hislop; Tom Marshall; Matthew Fay; Nadeem Qureshi; Daniel S Lasserson; Karen Kearley; Jill Mollison; Ly-Mee Yu; David Fitzmaurice; Fd Richard Hobbs
Journal:  Br J Gen Pract       Date:  2018-11-05       Impact factor: 5.386

Review 4.  Stroke prevention in nonvalvular atrial fibrillation.

Authors:  Leila Ganjehei; Ali Massumi; Mehdi Razavi; Abdi Rasekh
Journal:  Tex Heart Inst J       Date:  2011

5.  Prescribing warfarin appropriately to meet patient safety goals.

Authors:  Lekshmi Dharmarajan; T S Dharmarajan
Journal:  Am Health Drug Benefits       Date:  2008-07

Review 6.  Use of warfarin in long-term care: a systematic review.

Authors:  Marjorie Neidecker; Aarti A Patel; Winnie W Nelson; Gregory Reardon
Journal:  BMC Geriatr       Date:  2012-04-05       Impact factor: 3.921

7.  Anticoagulant Therapy for Frail Patients with Atrial Fibrillation.

Authors:  Hiroshi Hori; Takahiko Fukuchi; Hitoshi Sugawara
Journal:  Intern Med       Date:  2021-02-15       Impact factor: 1.271

8.  Qualitative study of willingness and demand for participation in decision-making regarding anticoagulation therapy in patient undergoing heart valve replacement.

Authors:  YaNing Zang; ShanShan Liu; YuHong Chen
Journal:  BMC Med Inform Decis Mak       Date:  2022-02-18       Impact factor: 2.796

9.  Warfarin for prevention of thrombosis among long-term care residents with atrial fibrillation: evidence of continuing low use despite consideration of stroke and bleeding risk.

Authors:  Gregory Reardon; Winnie W Nelson; Aarti A Patel; Tommy Philpot; Marjorie Neidecker
Journal:  Drugs Aging       Date:  2013-06       Impact factor: 3.923

  9 in total

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