Literature DB >> 16413299

Expression and properties of sorting nexin 9 in dynamin-mediated endocytosis.

Richard Lundmark1, Sven R Carlsson.   

Abstract

Sorting nexin 9 (SNX9) is identified as an important regulator of dynamin function in clathrin-mediated endocytosis. SNX9 recruits dynamin to the plasma membrane and promotes its GTPase activity, resulting in membrane constriction and ultimate transport vesicle scission. This chapter describes procedures to express recombinant SNX9, to biochemically characterize the cytosolic complex between SNX9 and dynamin, and to identify additional interacting partners of SNX9. Assays are presented to investigate the requirements for SNX9-dependent membrane recruitment of dynamin in vitro and in vivo.

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Year:  2005        PMID： 16413299     DOI： 10.1016/S0076-6879(05)04048-6

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  6 in total

1.  Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells.

Authors:  Nawal Bendris; Carrie J S Stearns; Carlos R Reis; Jaime Rodriguez-Canales; Hui Liu; Agnieszka W Witkiewicz; Sandra L Schmid
Journal:  J Cell Sci       Date:  2016-06-08       Impact factor: 5.285

Review 2.  Endocytosis, Metastasis and Beyond: Multiple Facets of SNX9.

Authors:  Nawal Bendris; Sandra L Schmid
Journal:  Trends Cell Biol       Date:  2016-12-16       Impact factor: 20.808

Review 3.  Dynamin 2 and human diseases.

Authors:  Anne-Cécile Durieux; Bernard Prudhon; Pascale Guicheney; Marc Bitoun
Journal:  J Mol Med (Berl)       Date:  2010-02-03       Impact factor: 4.599

Review 4.  Charcot-Marie-Tooth disease and intracellular traffic.

Authors:  Cecilia Bucci; Oddmund Bakke; Cinzia Progida
Journal:  Prog Neurobiol       Date:  2012-03-22       Impact factor: 11.685

5.  SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases.

Authors:  Nawal Bendris; Karla C Williams; Carlos R Reis; Erik S Welf; Ping-Hung Chen; Bénédicte Lemmers; Michael Hahne; H S Leong; Sandra L Schmid
Journal:  Mol Biol Cell       Date:  2016-03-09       Impact factor: 4.138

6.  Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation.

Authors:  Helene Knævelsrud; Kristiane Søreng; Camilla Raiborg; Karin Håberg; Fredrik Rasmuson; Andreas Brech; Knut Liestøl; Tor Erik Rusten; Harald Stenmark; Thomas P Neufeld; Sven R Carlsson; Anne Simonsen
Journal:  J Cell Biol       Date:  2013-07-22       Impact factor: 10.539
  6 in total

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