Literature DB >> 16412526

Quantification of phagocytosis of Aspergillus conidia by macrophages using a novel antibody-independent assay.

Kathrin Luther1, Manfred Rohde, Jürgen Heesemann, Frank Ebel.   

Abstract

The pathogenic mould Aspergillus fumigatus can cause severe infections in immunocompromised patients. Phagocytosis of inhaled conidia is an early and crucial event in the defense of A. fumigatus infections. Here we describe a novel antibody-independent assay for quantification of phagocytosis, that in this study has been applied to different Aspergillus species, but that is in principle suitable for many fungi.

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Year:  2006        PMID: 16412526     DOI: 10.1016/j.mimet.2005.11.008

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN: 0167-7012            Impact factor:   2.363


  5 in total

1.  Conidia but not yeast cells of the fungal pathogen Histoplasma capsulatum trigger a type I interferon innate immune response in murine macrophages.

Authors:  Diane O Inglis; Charlotte A Berkes; Davina R Hocking Murray; Anita Sil
Journal:  Infect Immun       Date:  2010-07-06       Impact factor: 3.441

2.  Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis.

Authors:  Sixto M Leal; Susan Cowden; Yen-Cheng Hsia; Mahmoud A Ghannoum; Michelle Momany; Eric Pearlman
Journal:  PLoS Pathog       Date:  2010-07-01       Impact factor: 6.823

3.  Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages.

Authors:  Silvia Slesiona; Markus Gressler; Michael Mihlan; Christoph Zaehle; Martin Schaller; Dagmar Barz; Bernhard Hube; Ilse D Jacobsen; Matthias Brock
Journal:  PLoS One       Date:  2012-02-03       Impact factor: 3.240

4.  In vitro determination of phagocytosis and intracellular killing of Aspergillus species by mononuclear phagocytes.

Authors:  Susanne Perkhofer; Cornelia Speth; Manfred P Dierich; Cornelia Lass-Flörl
Journal:  Mycopathologia       Date:  2007-04-26       Impact factor: 3.785

5.  Susceptibility to Aspergillus Infections in Rats with Chronic Obstructive Pulmonary Disease via Deficiency Function of Alveolar Macrophages and Impaired Activation of TLR2.

Authors:  Yuting Wu; Hong Xu; Li Li; Weifeng Yuan; Deming Zhang; Wenjie Huang
Journal:  Inflammation       Date:  2016-08       Impact factor: 4.092

  5 in total

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