OBJECTIVE: Data regarding the prevalence of Helicobacter pylori infection and its potential risk factors among schoolchildren from the Middle East is scarce. METHODS: An enzyme-linked immunosorbent assay was used to investigate H. pylori status in four groups of children: The first and second groups, 50 children each (25 boys, 25 girls) included children from high socioeconomic class (group 1 = 6 years old; group 2 = 9 years old). The third and fourth groups were sex- and age-matched, but from low socioeconomic class. To evaluate the association between the seroprevalence of H. pylori and selected risk factors, odds ratios (crude and adjusted) were calculated using multiple regression analysis. RESULTS: Overall seroprevalence rate was 55.5%. Seropositivity was 42%, 52%, 60%, and 68% for groups 1, 2, 3, and 4, respectively. Age and sex were not significantly associated with H. pylori seropositivity. In the final logistic regression model, which was adjusted for age and sex, the following risk factors were found to be significantly associated with seropositivity: living in rural areas (P = 0.015), poor sanitation (P < 0.001), overcrowding (P = 0.014), low maternal educational level (P = 0.010) and low socioeconomic status (P = 0.011). CONCLUSIONS: The prevalence of H. pylori infection in Jordanian schoolchildren is high, suggesting that most acquisition occurs before the age of 6 years. The seroprevalence for H. pylori increases with social deprivation.
OBJECTIVE: Data regarding the prevalence of Helicobacter pylori infection and its potential risk factors among schoolchildren from the Middle East is scarce. METHODS: An enzyme-linked immunosorbent assay was used to investigate H. pylori status in four groups of children: The first and second groups, 50 children each (25 boys, 25 girls) included children from high socioeconomic class (group 1 = 6 years old; group 2 = 9 years old). The third and fourth groups were sex- and age-matched, but from low socioeconomic class. To evaluate the association between the seroprevalence of H. pylori and selected risk factors, odds ratios (crude and adjusted) were calculated using multiple regression analysis. RESULTS: Overall seroprevalence rate was 55.5%. Seropositivity was 42%, 52%, 60%, and 68% for groups 1, 2, 3, and 4, respectively. Age and sex were not significantly associated with H. pylori seropositivity. In the final logistic regression model, which was adjusted for age and sex, the following risk factors were found to be significantly associated with seropositivity: living in rural areas (P = 0.015), poor sanitation (P < 0.001), overcrowding (P = 0.014), low maternal educational level (P = 0.010) and low socioeconomic status (P = 0.011). CONCLUSIONS: The prevalence of H. pyloriinfection in Jordanian schoolchildren is high, suggesting that most acquisition occurs before the age of 6 years. The seroprevalence for H. pylori increases with social deprivation.
Authors: Monica Contreras; Milagro Fernández-Delgado; Nelson Reyes; María Alexandra García-Amado; Héctor Rojas; Fabian Michelangeli Journal: Am J Trop Med Hyg Date: 2015-07-20 Impact factor: 2.345
Authors: Mohammad Hussain Hamrah; Mohammad Shoaib Hamrah; Mohammad Hassan Hamrah; Mitsuro Kanda; Ahmad Edris Hamrah; Ahmad Elias Dahi; Farhat Homayoun; Mohammad Hashem Hamrah; Akbar Fotouhi; Junichi Sakamoto Journal: Asian Pac J Cancer Prev Date: 2017-11-26
Authors: Eyad Altamimi; Noor Alsharkhat; Afnan AlJawarneh; Moh D Rawhi Abu Hamad; Anas Abu Assi; Sarah Alawneh; Majd Al-Ahmad Journal: Heliyon Date: 2020-07-20