Literature DB >> 16411595

Dendrimers for pharmaceutical and biomedical applications.

Hu Yang1, Weiyuan John Kao.   

Abstract

Dendrimers are a unique class of synthetic macromolecules having a highly branched, three-dimensional, nanoscale architecture with very low polydispersity and high functionality. Structural advantages allow dendrimers to play an important role in the fields of nanotechnology, pharmaceutical and medicinal chemistry. This review discusses several aspects of dendrimers, including preparation, dendrimer-drug coupling chemistry, structural models of dendrimer-based drug delivery systems, and physicochemical and toxicological properties.

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Year:  2006        PMID： 16411595     DOI： 10.1163/156856206774879171

Source DB:  PubMed          Journal:  J Biomater Sci Polym Ed        ISSN： 0920-5063            Impact factor:   3.517


  24 in total

1.  Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery.

Authors:  Quan Yuan; Eunmee Lee; W Andrew Yeudall; Hu Yang
Journal:  Oral Oncol       Date:  2010-08-21       Impact factor: 5.337

Review 2.  Novel nanomaterials for clinical neuroscience.

Authors:  Jamie L Gilmore; Xiang Yi; Lingdong Quan; Alexander V Kabanov
Journal:  J Neuroimmune Pharmacol       Date:  2008-01-22       Impact factor: 4.147

3.  Developmental toxicity of low generation PAMAM dendrimers in zebrafish.

Authors:  Tisha C King Heiden; Emelyne Dengler; Weiyuan John Kao; Warren Heideman; Richard E Peterson
Journal:  Toxicol Appl Pharmacol       Date:  2007-07-31       Impact factor: 4.219

4.  Synthesis and Application of Injectable Bioorthogonal Dendrimer Hydrogels for Local Drug Delivery.

Authors:  Leyuan Xu; Remy C Cooper; Juan Wang; W Andrew Yeudall; Hu Yang
Journal:  ACS Biomater Sci Eng       Date:  2017-06-21

5.  Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer.

Authors:  Mallory A van Dongen; Ankur Desai; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal:  Polymer (Guildf)       Date:  2013-07-19       Impact factor: 4.430

6.  Stealth dendrimers for drug delivery: correlation between PEGylation, cytocompatibility, and drug payload.

Authors:  Hu Yang; Stephanie T Lopina; Linda P DiPersio; Steven P Schmidt
Journal:  J Mater Sci Mater Med       Date:  2007-10-19       Impact factor: 3.896

7.  Synthesis and characterization of thermoresponsive polyamidoamine-polyethylene glycol-poly(D,L-lactide) core-shell nanoparticles.

Authors:  Arunvel Kailasan; Quan Yuan; Hu Yang
Journal:  Acta Biomater       Date:  2009-08-27       Impact factor: 8.947

Review 8.  Complex polyamines: unique prion disaggregating compounds.

Authors:  Surachai Supattapone; Justin R Piro; Judy R Rees
Journal:  CNS Neurol Disord Drug Targets       Date:  2009-11       Impact factor: 4.388

9.  Poly(amidoamine) dendrimers on lipid bilayers II: Effects of bilayer phase and dendrimer termination.

Authors:  Christopher V Kelly; Pascale R Leroueil; Bradford G Orr; Mark M Banaszak Holl; Ioan Andricioaei
Journal:  J Phys Chem B       Date:  2008-07-12       Impact factor: 2.991

10.  Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery.

Authors:  Hu Yang; Weiyuan John Kao
Journal:  Int J Nanomedicine       Date:  2007
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