Literature DB >> 16410135

Vacuum-assisted closure: a new method for treating patients with giant omphalocele.

Kandice E Kilbride1, Donald R Cooney, Monford D Custer.   

Abstract

INTRODUCTION: Closure of giant omphalocele can present a surgical challenge. Neither silo, skin flap, nor primary closure has been successful in treating all patients. We present a novel application of the vacuum-assisted closure (VAC) device, which allows for improved results in these difficult cases.
METHODS: The VAC device (KCI, San Antonio, Tex) consisted of a sponge applied directly to the bowel and liver, covered with impermeable transparent dressing, and attached to a low negative pressure system. The sponge was changed every 3 to 5 days under local sedation. PATIENTS: All 3 patients had giant omphaloceles. The first infant, a 34 week gestational age (WGA) male, was initially treated with silo reduction, which disrupted after 21 days. The large mass of bowel and liver made primary closure impossible. The VAC was applied for 45 days. The viscera was easily reduced and subsequently covered with acellular dermal matrix (AlloDerm). The VAC was reapplied, and the small remaining defect was skin-grafted. The second male infant was a 34 WGA male infant who became septic after failure of prosthetic mesh closure. The VAC was applied for 22 days after removal of the mesh. The infection resolved, and the defect size was reduced, allowing for skin flap closure. Mesh infection and development of an enterocutaneous fistula in the last patient, a 37 WGA female child, were treated by mesh removal and application of the VAC for 36 days. The VAC allowed for control of the fistula output and development of a healthy granulation bed.
RESULTS: Vacuum-assisted closure was associated with (1) rapid shrinkage and reduction of the viscera (22-45 days); (2) cleansing of the wound; (3) excellent granulation; (4) maintenance of a sterile environment; and (5) ease of use, with changes possible at the bedside.
CONCLUSION: The VAC device should be considered a safe and effective alternative in treating complicated cases of giant omphalocele until a more definitive closure method can be used.

Entities:  

Mesh:

Year:  2006        PMID: 16410135     DOI: 10.1016/j.jpedsurg.2005.10.003

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  11 in total

1.  Negative pressure wound therapy in the management of neonates with complex gastroschisis.

Authors:  Wilson W Choi; Craig A McBride; Roy M Kimble
Journal:  Pediatr Surg Int       Date:  2011-02-19       Impact factor: 1.827

2.  Negative pressure wound therapy facilitates closure of large congenital abdominal wall defects.

Authors:  Craig A McBride; Kellie Stockton; Kristen Storey; Roy M Kimble
Journal:  Pediatr Surg Int       Date:  2014-07-25       Impact factor: 1.827

Review 3.  Negative-Pressure Wound Therapy in Infants and Children: A Population-Based Study.

Authors:  Katherine B Santosa; Matt Keller; Margaret A Olsen; Alexandra M Keane; Erika D Sears; Alison K Snyder-Warwick
Journal:  J Surg Res       Date:  2018-11-30       Impact factor: 2.192

Review 4.  Review of the evidence on the closure of abdominal wall defects.

Authors:  Vincent E Mortellaro; Shawn D St Peter; Frankie B Fike; Saleem Islam
Journal:  Pediatr Surg Int       Date:  2010-12-14       Impact factor: 1.827

Review 5.  V.A.C. Therapy in the management of paediatric wounds: clinical review and experience.

Authors:  Mona Baharestani; Ibrahim Amjad; Kim Bookout; Tatjana Fleck; Allen Gabriel; David Kaufman; Shannon Stone McCord; Donald C Moores; Oluyinka O Olutoye; Jorge D Salazar; David H Song; Steven Teich; Subhas Gupta
Journal:  Int Wound J       Date:  2009-08       Impact factor: 3.315

6.  Exomphalos major: the Northern Ireland experience.

Authors:  P Charlesworth; E Ervine; M McCullagh
Journal:  Pediatr Surg Int       Date:  2008-11-12       Impact factor: 1.827

7.  Worst Prognosis in the "Complex" Jejunoileal Atresia: Is It Real?

Authors:  Silvana Federici; Maria Domenica Sabatino; Vincenzo Domenichelli; Simona Straziuso
Journal:  European J Pediatr Surg Rep       Date:  2014-07-17

8.  Giant omphalocele treated with intramuscular tissue expansion.

Authors:  Jacob Buinewicz; Donald Laub
Journal:  Eplasty       Date:  2014-01-16

9.  Management of a Giant Omphalocele with Non-Cross-Linked Intact Porcine-Derived Acellular Dermal Matrix (Strattice) Combined with Vacuum Therapy.

Authors:  Daisy Vieira Travassos; Albertien M van Eerde; William L M Kramer
Journal:  European J Pediatr Surg Rep       Date:  2015-06-26

10.  Is progressive pneumoperitoneum useful in delayed repair of large omphaloceles?

Authors:  Vivek Gharpure
Journal:  J Indian Assoc Pediatr Surg       Date:  2008-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.