Literature DB >> 16409004

Practical method for transforming alkynes into alpha-diketones.

Zhonghui Wan1, Chauncey D Jones, David Mitchell, John Y Pu, Tony Y Zhang.   

Abstract

[reaction: see text] Oxidation of alkynes to alpha-dicarbonyl derivatives through a convenient one-pot procedure via a Brønsted acid-promoted "hydration" and a DMSO-based oxidation sequence has been achieved in high yields. The scope and limitations of the reaction have also been investigated.

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Year:  2006        PMID： 16409004     DOI： 10.1021/jo051793g

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors.

Authors:  Brandon M Young; Janice L Hyatt; David C Bouck; Taosheng Chen; Parimala Hanumesh; Jeanine Price; Vincent A Boyd; Philip M Potter; Thomas R Webb
Journal:  J Med Chem       Date:  2010-11-24       Impact factor: 7.446

2.  Accessing Grignard Reluctant Aldehyde in 2-Oxoaldehyde by Organocuprates to Give [1,2] Addition and Oxidative Coupling Reactions.

Authors:  Satyanarayana Battula; Aman A Desai; Jigar Y Soni; Dhruv P Mehta
Journal:  ACS Omega       Date:  2022-02-01

3.  Gold-catalyzed oxidation of arylallenes: Synthesis of quinoxalines and benzimidazoles.

Authors:  Dong-Mei Cui; Dan-Wen Zhuang; Ying Chen; Chen Zhang
Journal:  Beilstein J Org Chem       Date:  2011-06-24       Impact factor: 2.883

4.  Synthesis of α-diketones from alkylaryl- and diarylalkynes using mercuric salts.

Authors:  Michael E Jung; Gang Deng
Journal:  Org Lett       Date:  2014-04-01       Impact factor: 6.005

5.  Synthesis of dimethyl aryl acylsulfonium bromides from aryl methyl ketones in a DMSO-HBr system.

Authors:  Zhiling Cao; Dahua Shi; Yingying Qu; Chuanzhou Tao; Weiwei Liu; Guowei Yao
Journal:  Molecules       Date:  2013-12-16       Impact factor: 4.411

Review 6.  Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms.

Authors:  Iván Cortés; L Javier Cala; Andrea B J Bracca; Teodoro S Kaufman
Journal:  RSC Adv       Date:  2020-09-10       Impact factor: 4.036
  6 in total

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