| Literature DB >> 16406419 |
Chunlei Fan1, Xingde Wo, Ying Qian, Jin Yin, Liping Gao.
Abstract
To investigate the molecular mechanisms of lipid-lowering drug, Rhizoma Curcumae Longae, we treated the mouse macrophages with curcumin, which was purified from the ethanol extraction of Rhizoma Curcumae Longae. The LDL receptors expressed in the macrophages were determined by ELISA, FLISA and assay of LDL uptake. Here for the first time, we found that curcumin obviously up-regulated the expression of LDL receptor in mouse macrophages, and the dose-effect relationship was demonstrated.Entities:
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Year: 2006 PMID： 16406419 DOI： 10.1016/j.jep.2005.11.009
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360