Literature DB >> 16406269

Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats.

Wei-Min Gao1, Mandeep S Chadha, Anthony E Kline, Robert S B Clark, Patrick M Kochanek, C Edward Dixon, Larry W Jenkins.   

Abstract

Posttranslational modifications (PTMs) of histone proteins may result in altered epigenetic signaling after pediatric traumatic brain injury (TBI). Hippocampal histone H3 acetylation and methylation in immature rats after moderate TBI were measured and decreased only in CA3 at 6 h and 24 h with persistent methylation decreases up to 72 h after injury. Decreased histone H3 acetylation and methylation suggest altered hippocampal CA3 epigenetic signaling during the first hours to days after TBI.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16406269      PMCID： PMC2721467          DOI： 10.1016/j.brainres.2005.11.038

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  23 in total

1.  Upregulation of iNOS expression and phosphorylation of eIF-2alpha are paralleled by suppression of protein synthesis in rat hypothalamus in a closed head trauma model.

Authors:  T Petrov; B D Underwood; B Braun; S S Alousi; J A Rafols
Journal:  J Neurotrauma       Date:  2001-08       Impact factor: 5.269

2.  Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/RSK cascade in insular cortex during novel taste learning.

Authors:  M W Swank; J D Sweatt
Journal:  J Neurosci       Date:  2001-05-15       Impact factor: 6.167

Review 3.  Controlling the double helix.

Authors:  Gary Felsenfeld; Mark Groudine
Journal:  Nature       Date:  2003-01-23       Impact factor: 49.962

Review 4.  Epigenetic mechanisms in memory formation.

Authors:  Jonathan M Levenson; J David Sweatt
Journal:  Nat Rev Neurosci       Date:  2005-02       Impact factor: 34.870

Review 5.  Do protein motifs read the histone code?

Authors:  Xavier de la Cruz; Sergio Lois; Sara Sánchez-Molina; Marian A Martínez-Balbás
Journal:  Bioessays       Date:  2005-02       Impact factor: 4.345

6.  Differential activation of mitogen-activated protein kinase pathways after traumatic brain injury in the rat hippocampus.

Authors:  Naoki Otani; Hiroshi Nawashiro; Shinji Fukui; Namiko Nomura; Akiko Yano; Takahito Miyazawa; Katsuji Shima
Journal:  J Cereb Blood Flow Metab       Date:  2002-03       Impact factor: 6.200

7.  The role of extracellular signal-regulated kinase in cognitive and motor deficits following experimental traumatic brain injury.

Authors:  P K Dash; S A Mach; A N Moore
Journal:  Neuroscience       Date:  2002       Impact factor: 3.590

8.  CBP histone acetyltransferase activity is a critical component of memory consolidation.

Authors:  Edward Korzus; Michael G Rosenfeld; Mark Mayford
Journal:  Neuron       Date:  2004-06-24       Impact factor: 17.173

9.  Biochemical, cellular, and molecular mechanisms in the evolution of secondary damage after severe traumatic brain injury in infants and children: Lessons learned from the bedside.

Authors:  Patrick M. Kochanek; Robert S.B. Clark; Randall A. Ruppel; P. David Adelson; Michael J. Bell; Michael J. Whalen; Courtney L. Robertson; Margaret A. Satchell; Neal A. Seidberg; Donald W. Marion; Larry W. Jenkins
Journal:  Pediatr Crit Care Med       Date:  2000-07       Impact factor: 3.624

10.  Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity.

Authors:  Grace Sophia Griesbach; David Allen Hovda; Raffaella Molteni; Fernando Gomez-Pinilla
Journal:  J Neurotrauma       Date:  2002-07       Impact factor: 5.269
View more
  35 in total

1.  Environmental chemical exposures and human epigenetics.

Authors:  Lifang Hou; Xiao Zhang; Dong Wang; Andrea Baccarelli
Journal:  Int J Epidemiol       Date:  2011-12-13       Impact factor: 7.196

2.  Gel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact.

Authors:  Ashley R Kochanek; Anthony E Kline; Wei-Min Gao; Mandeep Chadha; Yichen Lai; Robert S B Clark; C Edward Dixon; Larry W Jenkins
Journal:  Dev Neurosci       Date:  2006       Impact factor: 2.984

3.  IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.

Authors:  Matthew L Diamond; Anne C Ritter; Michelle D Failla; Jennifer A Boles; Yvette P Conley; Patrick M Kochanek; Amy K Wagner
Journal:  Epilepsia       Date:  2014-04-22       Impact factor: 5.864

4.  Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.

Authors:  Matthew L Diamond; Anne C Ritter; Edwin K Jackson; Yvette P Conley; Patrick M Kochanek; Detlev Boison; Amy K Wagner
Journal:  Epilepsia       Date:  2015-06-04       Impact factor: 5.864

Review 5.  Epigenetic changes following traumatic brain injury and their implications for outcome, recovery and therapy.

Authors:  Victor S Wong; Brett Langley
Journal:  Neurosci Lett       Date:  2016-05-04       Impact factor: 3.046

Review 6.  Epilepsy related to traumatic brain injury.

Authors:  Asla Pitkänen; Riikka Immonen
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

7.  Genetic variability in glutamic acid decarboxylase genes: associations with post-traumatic seizures after severe TBI.

Authors:  Shaun D Darrah; Megan A Miller; Dianxu Ren; Nichole Z Hoh; Joelle M Scanlon; Yvette P Conley; Amy K Wagner
Journal:  Epilepsy Res       Date:  2012-07-26       Impact factor: 3.045

8.  Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats.

Authors:  Pramod K Dash; Sara A Orsi; Min Zhang; Raymond J Grill; Shibani Pati; Jing Zhao; Anthony N Moore
Journal:  PLoS One       Date:  2010-06-30       Impact factor: 3.240

9.  HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats.

Authors:  Bin Zhang; Eric J West; Ken C Van; Gene G Gurkoff; Jia Zhou; Xiu-Mei Zhang; Alan P Kozikowski; Bruce G Lyeth
Journal:  Brain Res       Date:  2008-06-11       Impact factor: 3.252

10.  Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury.

Authors:  P K Dash; S A Orsi; A N Moore
Journal:  Neuroscience       Date:  2009-06-13       Impact factor: 3.590
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.