R Nicholas1, P D O'Meara, N Calonge. 1. Colorado Altitude Research Institute, Snake River Health Services, Keystone 80435.
Abstract
STUDY OBJECTIVE: To investigate factors related to syncope occurring on recent ascent to moderate altitude. DESIGN: A 1-year retrospective case-control study, using local acclimatized residents as a control group. SETTING: The two main ambulance destinations for Summit County, Colorado (elevation, 2770 m). PATIENTS: All patients with a diagnosis of syncope, near-syncope, or fainting whose medical records were available for review. RESULTS: There was a significant relationship (P less than .05) between syncope of unknown origin and recent arrival at altitude (less than 24 hours), and a significant inverse relationship (P less than .05) between syncope of unknown origin and arterial oxygen saturation as measured by pulse oximetry. CONCLUSIONS: Short-term exposure to moderate altitude may be related to otherwise unexplained syncope in healthy young adults. We suggest the name high-altitude syncope for this entity and encourage further research in this area.
STUDY OBJECTIVE: To investigate factors related to syncope occurring on recent ascent to moderate altitude. DESIGN: A 1-year retrospective case-control study, using local acclimatized residents as a control group. SETTING: The two main ambulance destinations for Summit County, Colorado (elevation, 2770 m). PATIENTS: All patients with a diagnosis of syncope, near-syncope, or fainting whose medical records were available for review. RESULTS: There was a significant relationship (P less than .05) between syncope of unknown origin and recent arrival at altitude (less than 24 hours), and a significant inverse relationship (P less than .05) between syncope of unknown origin and arterial oxygen saturation as measured by pulse oximetry. CONCLUSIONS: Short-term exposure to moderate altitude may be related to otherwise unexplained syncope in healthy young adults. We suggest the name high-altitude syncope for this entity and encourage further research in this area.
Authors: Noud van Helmond; Blair D Johnson; Walter W Holbein; Humphrey G Petersen-Jones; Ronée E Harvey; Sushant M Ranadive; Jill N Barnes; Timothy B Curry; Victor A Convertino; Michael J Joyner Journal: Physiol Rep Date: 2018-02
Authors: William K Cornwell; Aaron L Baggish; Yadav Kumar Deo Bhatta; Maria Joan Brosnan; Christoph Dehnert; J Sawalla Guseh; Debra Hammer; Benjamin D Levine; Gianfranco Parati; Eugene E Wolfel Journal: J Am Heart Assoc Date: 2021-09-09 Impact factor: 5.501