OBJECTIVE: To discuss methodological factors that account for the wide variation in the reported prevalence rates of anomalies associated with oral clefts. CONCLUSIONS: The published prevalences of associated anomalies vary considerably because of the following: (1) differences in case definition and inclusion/exclusion criteria; (2) length of time after birth that cases are examined; (3) variability of clinical expression of associated anomalies; (4) knowledge and technology available to produce syndrome delineation; (5) selection of patients, sources of ascertainment, and sample size; and (6) true population differences and changes in frequency over time.
OBJECTIVE: To discuss methodological factors that account for the wide variation in the reported prevalence rates of anomalies associated with oral clefts. CONCLUSIONS: The published prevalences of associated anomalies vary considerably because of the following: (1) differences in case definition and inclusion/exclusion criteria; (2) length of time after birth that cases are examined; (3) variability of clinical expression of associated anomalies; (4) knowledge and technology available to produce syndrome delineation; (5) selection of patients, sources of ascertainment, and sample size; and (6) true population differences and changes in frequency over time.
Authors: Monica Rittler; Viviana Cosentino; Jorge S López-Camelo; Jeffrey C Murray; George Wehby; Eduardo E Castilla Journal: Am J Med Genet A Date: 2011-06-10 Impact factor: 2.802
Authors: Maria Luisa Navarro Sanchez; Renata H Benjamin; Laura E Mitchell; Peter H Langlois; Mark A Canfield; Michael D Swartz; Angela E Scheuerle; Daryl A Scott; Hope Northrup; Christian P Schaaf; Joseph W Ray; Scott D McLean; Han Chen; Philip J Lupo; A J Agopian Journal: Cleft Palate Craniofac J Date: 2021-04-28
Authors: Alice V Pereira; Nuno Fradinho; Sara Carmo; Juliana M de Sousa; David Rasteiro; Regina Duarte; Maria J Leal Journal: Plast Reconstr Surg Glob Open Date: 2018-02-09