Literature DB >> 16405003

Experimental assessment of the pathogenicity of H5N1 influenza A viruses isolated in Japan.

Masaji Mase1, Tadao Imada, Kikuyasu Nakamura, Nobuhiko Tanimura, Kunitoshi Imai, Kenji Tsukamoto, Shigeo Yamaguchi.   

Abstract

We examined the pathogenicity for chickens of two H5N1 avian influenza viruses isolated in Japan, A/chicken/ Yamaguchi/7/2004 (Ck/Yamaguchi/7/04) isolated from outbreaks in commercial layer chickens, and A/duck/Yokohama/aq10/ 2003 (Dk/Yokohama/aq10/03) isolated from duck meat imported from China. All chickens inoculated intranasally with either strain died, and the viruses were reisolated from all organs examined. However, both the mean time of onset of clinical signs and the mean death time of Ck/Yamaguchi/7/04 were shorter than those of Dk/Yokohama/aq10/03.

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Year:  2005        PMID： 16405003     DOI： 10.1637/7364-041105R.1

Source DB:  PubMed          Journal:  Avian Dis        ISSN： 0005-2086            Impact factor:   1.577


  4 in total

1.  Epidemiological consequences of an incursion of highly pathogenic H5N1 avian influenza into the British poultry flock.

Authors:  Kieran J Sharkey; Roger G Bowers; Kenton L Morgan; Susan E Robinson; Robert M Christley
Journal:  Proc Biol Sci       Date:  2008-01-07       Impact factor: 5.349

2.  Association of increased pathogenicity of Asian H5N1 highly pathogenic avian influenza viruses in chickens with highly efficient viral replication accompanied by early destruction of innate immune responses.

Authors:  Koutaro Suzuki; Hironao Okada; Toshihiro Itoh; Tatsuya Tada; Masaji Mase; Kikuyasu Nakamura; Masanori Kubo; Kenji Tsukamoto
Journal:  J Virol       Date:  2009-05-20       Impact factor: 5.103

3.  Increased inducible nitric oxide synthase expression in organs is associated with a higher severity of H5N1 influenza virus infection.

Authors:  Simon Burggraaf; John Bingham; Jean Payne; Wayne G Kimpton; John W Lowenthal; Andrew G D Bean
Journal:  PLoS One       Date:  2011-01-19       Impact factor: 3.240

4.  Scientific Report of the Scientific Panel on Biological Hazards on "Food as a possible source of infection with highly pathogenic avian influenza viruses for humans and other mammals".

Authors: 
Journal:  EFSA J       Date:  2006-03-22
  4 in total

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