Literature DB >> 16403697

Central executive system impairment in traumatic brain injury.

Andrea Serino1, Elisa Ciaramelli, Anna Di Santantonio, Susanna Malagù, Franco Servadei, Elisabetta Làdavas.   

Abstract

PRIMARY
OBJECTIVE: This study investigated whether cognitive impairment after traumatic brain injury (TBI) can be considered a consequence of (1) a speed processing deficit or (2) an impairment of the Central Executive System (CES) of working memory. METHODS AND PROCEDURES: Thirty-seven TBI patients underwent a standardized battery of neuropsychological tests evaluating speed processing, sustained attention, short-term memory, working memory, divided attention, executive functions and long-term memory. MAIN OUTCOMES AND
RESULTS: Patients showed severe deficits in working memory, divided attention, executive functions and long-term memory. Divided attention, long-term memory and executive functions deficits significantly correlated with working memory, but not with speed processing deficits. Moreover, multiple regression analyses showed that a CES impairment and not a speed processing deficit predicted divided attention, executive functions and long-term memory deficits. The severity and the site of brain lesions did not predict the level of CES or speed processing impairment.
CONCLUSIONS: The cognitive impairment following TBI seem to be caused by an impairment of the Central Executive System, rather than a speed processing deficit.

Entities:  

Mesh:

Year:  2006        PMID: 16403697     DOI: 10.1080/02699050500309627

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  11 in total

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4.  Joint analysis of frontal theta synchrony and white matter following mild traumatic brain injury.

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5.  Impaired theory of mind in adults with traumatic brain injury: A replication and extension of findings.

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8.  White matter and neurocognitive changes in adults with chronic traumatic brain injury.

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Journal:  J Int Neuropsychol Soc       Date:  2009-01       Impact factor: 2.892

9.  White matter integrity in veterans with mild traumatic brain injury: associations with executive function and loss of consciousness.

Authors:  Scott F Sorg; Lisa Delano-Wood; Norman Luc; Dawn M Schiehser; Karen L Hanson; Daniel A Nation; Elisa Lanni; Amy J Jak; Kun Lu; M J Meloy; Lawrence R Frank; James B Lohr; Mark W Bondi
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10.  Reduced amygdala volume is associated with deficits in inhibitory control: a voxel- and surface-based morphometric analysis of comorbid PTSD/mild TBI.

Authors:  B E Depue; J H Olson-Madden; H R Smolker; M Rajamani; L A Brenner; M T Banich
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