Literature DB >> 1640344

Colorectal carcinoma in children.

R A Brown1, H Rode, A J Millar, C Sinclair-Smith, S Cywes.   

Abstract

An increasing incidence of colorectal carcinoma has been noted at this institution. We report seven children with colorectal carcinoma. The average delay between onset of symptoms and diagnosis was 41/2 months, and in five patients distant metastases were present at the first operation. Initial symptoms were ignored in all cases and in only one was the serious nature of the condition realized at first presentation. In five lesions the histology was mucin secreting adenocarcinoma, a poor prognostic variant. All seven died on average 11 months after diagnosis. These three factors--delay in diagnosis, advanced stage of disease, and poorly differentiated histology--contribute overall to a poor prognosis in the young.

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Year:  1992        PMID: 1640344     DOI: 10.1016/0022-3468(92)90399-r

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  11 in total

1.  Colorectal carcinoma.

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Review 5.  Epidemiology and management options for colorectal cancer in children.

Authors:  Raya Saab; Wayne L Furman
Journal:  Paediatr Drugs       Date:  2008       Impact factor: 3.022

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8.  Colon carcinoma in children and adolescents: prognostic factors and outcome-a review of 11 cases.

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9.  Colon carcinoma in the adolescent.

Authors:  G Sebbag; L Lantsberg; A Arish; I Levi; J Hoda
Journal:  Pediatr Surg Int       Date:  1997-07       Impact factor: 1.827

10.  First-decade patient with colorectal cancer carrying both germline and somatic mutations in APC gene.

Authors:  Yung-Sung Yeh; Yu-Tang Chang; Cheng-Jen Ma; Ching-Wen Huang; Hsiang-Lin Tsai; Yi-Ting Chen; Jaw-Yuan Wang
Journal:  BMC Cancer       Date:  2017-12-14       Impact factor: 4.430

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