Literature DB >> 16403042

Comorbid behavioural problems in Tourette's syndrome are positively correlated with the severity of tic symptoms.

Yan Zhu1, Kai Man Leung, Po-zi Liu, Ming Zhou, Lin-yan Su.   

Abstract

OBJECTIVE: We studied the comorbid behavioural and mood problems in children with non-psychiatric Tourette's syndrome (TS) and their relationship with severity of tic disorder.
METHOD: Sixty-nine TS children and 69 healthy controls were assessed by Child Behavior Checklist (CBCL) and Yale Global Tic Severity Scale (YGTSS). The relationships between behavioural problems and severity of tic symptoms were analysed statistically by comparison, correlation and multiple linear regression.
RESULTS: Tourette's syndrome patients scored significantly lower (p<0.01) on the CBCL competency subscales and total score, and higher on all behavioural problem subscales and total score (p<0.01). Expectedly, the TS children had lower social competence than normal children. Among the TS children, the severity of tic symptoms is positively correlated with the severity of overall impairment in school and social competence. When the behavioural and mood problems commonly associated with TS were studied in detail, we found that delinquent behaviour, thought problems, attention problems, aggressive behaviour and externalizing are positively correlated with severity of tic symptoms.
CONCLUSION: The findings indicated that children with TS-only also had a broad range of behavioural problems, and some of these were related to the severity of tic symptoms.

Entities:  

Mesh:

Year:  2006        PMID: 16403042     DOI: 10.1080/j.1440-1614.2006.01745.x

Source DB:  PubMed          Journal:  Aust N Z J Psychiatry        ISSN: 0004-8674            Impact factor:   5.744


  9 in total

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Authors:  Andrea E Cavanna; Chiara Luoni; Claudia Selvini; Rosanna Blangiardo; Clare M Eddy; Paola R Silvestri; Paola V Cali'; Emanuela Gagliardi; Umberto Balottin; Francesco Cardona; Renata Rizzo; Cristiano Termine
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9.  Randomized controlled clinical trial comparing the efficacy and tolerability of aripiprazole and sodium valproate in the treatment of Tourette syndrome.

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  9 in total

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