Literature DB >> 16402826

Total synthesis of UCS1025A.

Tristan H Lambert1, Samuel J Danishefsky.   

Abstract

The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves a remarkable boron Reformatsky coupling of iodolactone 13 and aldehyde 17.

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Year:  2006        PMID： 16402826     DOI： 10.1021/ja0574567

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  15 in total

Review 1.  Human telomerase inhibitors from microbial source.

Authors:  Kalarikkal Gopikrishnan Kiran; Muthusamy Palaniswamy; Jayaraman Angayarkanni
Journal:  World J Microbiol Biotechnol       Date:  2015-07-01       Impact factor: 3.312

Review 2.  A brief history of antibiotics and select advances in their synthesis.

Authors:  Kyriacos C Nicolaou; Stephan Rigol
Journal:  J Antibiot (Tokyo)       Date:  2017-07-05       Impact factor: 2.649

3.  Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine.

Authors:  K C Nicolaou; Stephan Rigol
Journal:  Nat Prod Rep       Date:  2020-04-22       Impact factor: 13.423

4.  Total synthesis of taxane terpenes: cyclase phase.

Authors:  Yoshihiro Ishihara; Abraham Mendoza; Phil S Baran
Journal:  Tetrahedron       Date:  2013-07-08       Impact factor: 2.457

5.  Total Synthesis and Structural Revision of Antibiotic CJ-16,264.

Authors:  K C Nicolaou; Akshay A Shah; Henry Korman; Tabrez Khan; Lei Shi; Wisuttaya Worawalai; Emmanuel A Theodorakis
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-19       Impact factor: 15.336

6.  Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids.

Authors:  Li Li; Man-Cheng Tang; Shoubin Tang; Shushan Gao; Sameh Soliman; Leibniz Hang; Wei Xu; Tao Ye; Kenji Watanabe; Yi Tang
Journal:  J Am Chem Soc       Date:  2018-02-02       Impact factor: 15.419

7.  Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents.

Authors:  K C Nicolaou; Kiran Kumar Pulukuri; Stephan Rigol; Marek Buchman; Akshay A Shah; Nicholas Cen; Megan D McCurry; Kathryn Beabout; Yousif Shamoo
Journal:  J Am Chem Soc       Date:  2017-10-24       Impact factor: 15.419

8.  Computational planning of the synthesis of complex natural products.

Authors:  Barbara Mikulak-Klucznik; Patrycja Gołębiowska; Alison A Bayly; Oskar Popik; Tomasz Klucznik; Sara Szymkuć; Ewa P Gajewska; Piotr Dittwald; Olga Staszewska-Krajewska; Wiktor Beker; Tomasz Badowski; Karl A Scheidt; Karol Molga; Jacek Mlynarski; Milan Mrksich; Bartosz A Grzybowski
Journal:  Nature       Date:  2020-10-13       Impact factor: 49.962

9.  Total Synthesis of (-)-Spinosyn A via Carbonylative Macrolactonization.

Authors:  Yu Bai; Xingyu Shen; Yong Li; Mingji Dai
Journal:  J Am Chem Soc       Date:  2016-08-17       Impact factor: 15.419

Review 10.  Building trans-bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development.

Authors:  Wanli Zhang; Anna R Kaplan; Emma K Davison; Jared L Freeman; Margaret A Brimble; William M Wuest
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 13.423
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