Literature DB >> 16402235

Gabapentin in the treatment of severe sweating experienced by advanced cancer patients.

Giampiero Porzio1, Federica Aielli, Lucilla Verna, Claudio Porto, Paolo Aloisi, Katia Cannita, Enrico Ricevuto, Paolo Marchetti, Corrado Ficorella.   

Abstract

Nine patients with advanced cancer suffering from idiopathic severe sweating were treated with gabapentin (600-1,800 mg/day). All patients responded to the treatment; five patients experienced transient drowsiness. Gabapentin seems to be a safe and effective treatment for idiopathic sweating in advanced cancer patients. Further studies are warranted to confirm or refute these results.

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Year:  2006        PMID: 16402235     DOI: 10.1007/s00520-005-0014-5

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  16 in total

1.  Flushing and sweating in an advanced breast cancer patient relieved by olanzapine.

Authors:  Zbigniew Zylicz; Malgorzata Krajnik
Journal:  J Pain Symptom Manage       Date:  2003-06       Impact factor: 3.612

2.  Thioridazine in the management of cancer-related sweating.

Authors:  J Cowap; J Hardy
Journal:  J Pain Symptom Manage       Date:  1998-05       Impact factor: 3.612

3.  Gabapentin for hot flashes in 420 women with breast cancer: a randomised double-blind placebo-controlled trial.

Authors:  Kishan J Pandya; Gary R Morrow; Joseph A Roscoe; Hongwei Zhao; Jane T Hickok; Eduardo Pajon; Thomas J Sweeney; Tarit K Banerjee; Patrick J Flynn
Journal:  Lancet       Date:  2005 Sep 3-9       Impact factor: 79.321

Review 4.  Gabapentin for neuropathic pain: systematic review of controlled and uncontrolled literature.

Authors:  M A Mellegers; A D Furlan; A Mailis
Journal:  Clin J Pain       Date:  2001-12       Impact factor: 3.442

5.  A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.

Authors:  N Tsavaris; A Zinelis; A Karabelis; D Beldecos; C Bacojanis; N Milonacis; N Karvounis; P Kosmidis
Journal:  J Intern Med       Date:  1990-11       Impact factor: 8.989

6.  Gabapentin for the management of hot flushes: a case series.

Authors:  Paola Albertazzi; Mirella Bottazzi; David W Purdie
Journal:  Menopause       Date:  2003 May-Jun       Impact factor: 2.953

7.  Gabapentin for hot flashes in prostate cancer.

Authors:  Sean M Jeffery; Jeffrey J Pepe; Lisa M Popovich; Gail Vitagliano
Journal:  Ann Pharmacother       Date:  2002-03       Impact factor: 3.154

Review 8.  Fever and sweats in the patient with advanced cancer.

Authors:  Donna S Zhukovsky
Journal:  Hematol Oncol Clin North Am       Date:  2002-06       Impact factor: 3.722

9.  Megestrol acetate for the prevention of hot flashes.

Authors:  C L Loprinzi; J C Michalak; S K Quella; J R O'Fallon; A K Hatfield; R A Nelimark; A M Dose; T Fischer; C Johnson; N E Klatt
Journal:  N Engl J Med       Date:  1994-08-11       Impact factor: 91.245

10.  Hot flashes refractory to HRT and SSRI therapy but responsive to gabapentin therapy.

Authors:  Thomas Guttuso
Journal:  J Pain Symptom Manage       Date:  2004-03       Impact factor: 3.612

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  1 in total

Review 1.  Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management.

Authors:  William P Cheshire; Robert D Fealey
Journal:  Drug Saf       Date:  2008       Impact factor: 5.606

  1 in total

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